About Chana Sacks

Chana Sacks

All posts by Chana Sacks

CDX2 as a Prognostic Biomarker in Colon Cancer

• January 20th, 2016

A few weeks apart, Mr. Green and Mrs. Brown presented to their primary care doctors with intermittent rectal bleeding.  Both were referred for colonoscopies, and each was found to have a colonic mass.  With great trepidation, they awaited the results of the pathology and the CT scans that followed.  Ultimately, both were diagnosed with stage-II… Read More…


Remote Ischemic Preconditioning in Cardiac Surgery

• October 7th, 2015

In a lab at Duke University in 1986, scientists conducted an experiment comparing two different ways to give a dog a heart attack. The investigators cut off the blood flow of the circumflex artery for 40 minutes in 12 dogs. For 7 of those dogs, they first initiated a “preconditioning” protocol that consisted of four 5-minute… Read More…


Ezetimibe and Cardiovascular Outcomes

• June 3rd, 2015

As you walk into Mr. R’s room to see if he has last-minute questions about his discharge medications, you can’t believe how different – how much better – he looks dressed in his usual clothes, instead of an errantly-snapped hospital gown.   You met him 4 days ago, when he was wheeled, pale and groggy, onto… Read More…


Antimicrobial Therapy for Intraabdominal Infection

• May 20th, 2015

When the paramedics wheeled Mr. L into the Emergency Department, you knew exactly what to do.  Low blood pressure: establish good IV access and start fluids. Fever of 102 and left lower quadrant abdominal pain: obtain blood cultures, order antibiotics, and get him to the CT scanner once his vitals stabilize. In medical school, you think… Read More…


Prednisolone or Pentoxifylline for Alcoholic Hepatitis

• April 22nd, 2015

Intern year, they say, is about learning to distinguish “sick” from “not sick.” As the intern on-call overnight, you call the Emergency Department physician for pass off on Mr. Jones; when you hear “46-year-old man with heavy alcohol use disorder presenting with new jaundice and mild confusion,” it takes you only a split second to recognize… Read More…


Effects of Red-Cell Storage Duration on Patients Undergoing Cardiac Surgery

• April 8th, 2015

“Age,” the great boxer Muhammad Ali famously said, “is whatever you think it is. You are as old as you think you are.” The role that aging plays in vitality, strength, and wisdom has long been debated, but more recently the question of whether younger is better has been raised about red blood cells.  Currently, blood… Read More…


CABG or PCI in Patients with Coronary Disease?

• March 16th, 2015

The great singer Whitney Houston posed a question over 25 years ago that many still ponder today.  “Where,” she asked, “do broken hearts go?” Of course, her classic song asks us to imagine a destination for the pain wrought by the dissolution of love.  Physicians, however, have more concrete possibilities in mind when asking where to… Read More…


Improved Air Quality and Lung Development in Children

• March 4th, 2015

In 1905, the Public Health Congress convened in London, where Dr. Henry Antoine des Voeux presented a paper entitled “Fog and Smoke.”  In it, he described the characteristic black smoky fog – or “smog” – that enveloped London and many of the world’s other urban centers.  Credited with coining this new term, Dr. des Voeux… Read More…


Peanut Consumption in Infants at Risk for Peanut Allergy

• February 23rd, 2015

In a famous “Peanuts” cartoon, a glum Charlie Brown sits alone on a bench, eating a sandwich; his thought bubble reads, “Nothing takes the taste out of peanut butter quite like unrequited love.”  Charles Schulz was perhaps better than any other at simply and brilliantly capturing the timeless angst that defines the human condition. And… Read More…


Preexposure Prophylaxis for HIV-1 Infection

• February 4th, 2015

In December 2007, Elizabeth Mataka, the United Nations Special Envoy for HIV/AIDS in Africa, highlighted one of many stark realities of the HIV epidemic: “61% of all those living with HIV in Africa are women,” she wrote. “And 26 years into the epidemic, we know that underpinning this terrible statistic is gender inequality.” Condoms work. But… Read More…