Posts Tagged ‘anemia’

A Woman with Gastrointestinal Symptoms, Anemia, and Acute Kidney Injury

Posted by Sara Fazio • January 24th, 2014

In the latest Case Record of the Massachusetts General Hospital, a 61-year-old woman was admitted to the hospital because of vomiting, diarrhea, anemia, and acute kidney injury. Physical examination was normal. Laboratory testing and a diagnostic procedure were performed. The causes of rapidly progressive glomerulonephritis consist of the following three large groups of diseases: anti-glomerular… Read More…

Anemia and Thrombocytopenia

Posted by Sara Fazio • November 21st, 2013

In the latest Case Record of the Massachusetts General Hospital, a 38-year-old woman was admitted to this hospital because of fatigue, malaise, and lightheadedness, with dyspnea on exertion, bruising, dark urine, and headache. Laboratory tests revealed anemia and thrombocytopenia. Diagnostic tests were performed. Hemolytic anemia associated with normal red cells can be caused by destruction… Read More…

Anemia and Jaundice

Posted by Sara Fazio • June 28th, 2013

In the latest Case Record of the Massachusetts General Hospital, a 29-year-old man was admitted to the hospital because of anemia, jaundice, fatigue, and diffuse body aches. He had returned from a 3-month trip to North Africa 1 month before presentation. A diagnostic test was performed. Obtaining a thorough family history with particular attention to… Read More…

12-Year-Old Girl with Irritability and Insomnia

Posted by Sara Fazio • May 24th, 2013

In the latest Case Record of the Massachusetts General Hospital, a 12-year-old girl with a history of celiac disease, anxiety, and depression was seen in the outpatient psychiatry clinic of this hospital because of irritability, hypersomnia, and multiple somatic symptoms. Psychotherapy and the administration of antidepressants were begun. Pediatric patients with somatization are likely to… Read More…

Hepatitis C Virus Infection

Posted by Sara Fazio • May 17th, 2013

Only 20 years after the discovery of the hepatitis C virus, a cure is now likely for most people with chronic infection. The latest review in our Drug Therapy series considers current therapy and the present landscape of drug development for hepatitis C. The hepatitis C virus (HCV) carries a substantial disease burden, not only… Read More…

Peginesatide in Patients Undergoing Hemodialysis

Posted by Sara Fazio • January 25th, 2013

In two new randomized, controlled studies involving patients undergoing long-term hemodialysis, peginesatide, a synthetic peptide-based erythropoiesis-stimulating agent, was compared with epoetin for the treatment of anemia. The two agents were similarly effective.  Read both the EMERALD study and the PEARL study here. Partial correction of anemia with erythropoiesis-stimulating agents (ESAs) is a cornerstone of therapy… Read More…

Paresthesias and Anemia

Posted by Sara Fazio • April 25th, 2012

In the latest Case Record of the Massachusetts General Hospital, a 62-year-old man was admitted to this hospital because of paresthesias, weight loss, jaundice, and anemia. Diagnostic test results were received. Paresthesias involve a sensation of tingling, numbness, crawling, or deadness, and they are felt mainly in distal parts of the extremities. Although they very rarely involve… Read More…

Scleroderma Renal Crisis

Posted by Graham McMahon • September 30th, 2011

In the latest Case Record of the Massachusetts General Hospital, a 62-year-old woman with autoimmune overlap syndrome and polymyositis presented with anemia, thrombocytopenia, and acute renal failure. Four days before admission, she was found on the floor of her home, confused and minimally conversant.                                Approximately 70% of patients with diffuse cutaneous systemic sclerosis have kidney involvement,… Read More…

Microcytosis

Posted by Graham McMahon • August 19th, 2011

In the latest Case Record of the Massachusetts General Hospital, a 62-year-old woman presented with dyspnea, anemia, and paraspinal masses. Examination revealed splenomegaly. Laboratory studies revealed microcytic anemia. A diagnostic test result was received. A common feature of all thalassemias is that clinical symptoms arise less from the deficit in hemoglobin production than from the accumulation… Read More…