Posts Tagged ‘anemia’

Take the Case Challenge: A Man with Acute Liver Injury

Posted by • November 14th, 2016

A 50-year-old man was admitted to the hospital because of increased levels of aminotransferases, hyperbilirubinemia, anemia, and acute kidney injury. What is the most likely diagnosis? Read the case description then vote and comment on what you think the diagnosis is. Review the answers in the full text of the case to be published in the… Read More…

Iron-Deficiency Anemia

Posted by • May 8th, 2015

Iron-deficiency anemia is the most common form of anemia in the world. A new review article covers the global nature of the disease, iron homeostasis in normal and iron-deficient states, clinical findings, treatment, and causes of iron-resistant iron deficiency. Iron is crucial to biologic functions, including respiration, energy production, DNA synthesis, and cell proliferation. Although the… Read More…

Microcytic Anemia

Posted by • October 3rd, 2014

A new review discusses diagnosis and treatment of thalassemia, anemia of inflammation, and iron-deficiency anemia, highlighting recent findings.  The article includes an interactive graphic that shows various types of red cells that are observed in microcytic anemias and other conditions. The microcytic anemias are those characterized by the production of red cells that are smaller than… Read More…

A Woman with Gastrointestinal Symptoms, Anemia, and Acute Kidney Injury

Posted by • January 24th, 2014

In the latest Case Record of the Massachusetts General Hospital, a 61-year-old woman was admitted to the hospital because of vomiting, diarrhea, anemia, and acute kidney injury. Physical examination was normal. Laboratory testing and a diagnostic procedure were performed. The causes of rapidly progressive glomerulonephritis consist of the following three large groups of diseases: anti-glomerular basement… Read More…

Anemia and Thrombocytopenia

Posted by • November 21st, 2013

In the latest Case Record of the Massachusetts General Hospital, a 38-year-old woman was admitted to this hospital because of fatigue, malaise, and lightheadedness, with dyspnea on exertion, bruising, dark urine, and headache. Laboratory tests revealed anemia and thrombocytopenia. Diagnostic tests were performed. Hemolytic anemia associated with normal red cells can be caused by destruction of… Read More…

Anemia and Jaundice

Posted by • June 28th, 2013

In the latest Case Record of the Massachusetts General Hospital, a 29-year-old man was admitted to the hospital because of anemia, jaundice, fatigue, and diffuse body aches. He had returned from a 3-month trip to North Africa 1 month before presentation. A diagnostic test was performed. Obtaining a thorough family history with particular attention to hereditary… Read More…

12-Year-Old Girl with Irritability and Insomnia

Posted by • May 24th, 2013

In the latest Case Record of the Massachusetts General Hospital, a 12-year-old girl with a history of celiac disease, anxiety, and depression was seen in the outpatient psychiatry clinic of this hospital because of irritability, hypersomnia, and multiple somatic symptoms. Psychotherapy and the administration of antidepressants were begun. Pediatric patients with somatization are likely to have… Read More…

Hepatitis C Virus Infection

Posted by • May 17th, 2013

Only 20 years after the discovery of the hepatitis C virus, a cure is now likely for most people with chronic infection. The latest review in our Drug Therapy series considers current therapy and the present landscape of drug development for hepatitis C. The hepatitis C virus (HCV) carries a substantial disease burden, not only in… Read More…

Peginesatide in Patients Undergoing Hemodialysis

Posted by • January 25th, 2013

In two new randomized, controlled studies involving patients undergoing long-term hemodialysis, peginesatide, a synthetic peptide-based erythropoiesis-stimulating agent, was compared with epoetin for the treatment of anemia. The two agents were similarly effective.  Read both the EMERALD study and the PEARL study here. Partial correction of anemia with erythropoiesis-stimulating agents (ESAs) is a cornerstone of therapy for… Read More…

Paresthesias and Anemia

Posted by • April 25th, 2012

In the latest Case Record of the Massachusetts General Hospital, a 62-year-old man was admitted to this hospital because of paresthesias, weight loss, jaundice, and anemia. Diagnostic test results were received. Paresthesias involve a sensation of tingling, numbness, crawling, or deadness, and they are felt mainly in distal parts of the extremities. Although they very rarely involve the… Read More…