Posts Tagged ‘ARDS’

Simvastatin in the Acute Respiratory Distress Syndrome

Posted by Sara Fazio • October 31st, 2014

In a recent study, patients with acute respiratory distress syndrome who were not receiving statins were assigned to receive simvastatin or placebo. At 28 days, there were no significant between-group differences in survival or in the number of ventilator-free days. The acute respiratory distress syndrome (ARDS) is a common, devastating clinical syndrome characterized by life-threatening… Read More…

Severe Sepsis and Septic Shock

Posted by Sara Fazio • August 30th, 2013

Sepsis, a complex physiological and metabolic response to infection, is a common reason for admission to an intensive care unit. The first article in our Critical Care Medicine review series examines the basis, diagnosis, and current treatment of this disorder. In 1992, an international consensus panel defined sepsis as a systemic inflammatory response to infection,… Read More…

The Truth Behind the Lie: Prone Positioning in Severe Acute Respiratory Distress Syndrome

Posted by John Staples • June 5th, 2013

Physicians have long realized that a little change in position can go a long way. Is Mr. X’s peripheral arterial disease causing him ischemic rest pain? Keep those legs dependant. Is Mrs. Y getting orthopnea from uncontrolled heat failure? Sit her up and she might get some relief. Is the sight of blood making your… Read More…

New evidence that high-frequency oscillation not beneficial for ARDS patients (and may even be harmful)

Posted by Rachel Wolfson • February 27th, 2013

In the 1980s, a paradigm shift in the treatment of acute respiratory distress syndrome (ARDS) occurred: researchers found that decreasing tidal volumes provided by mechanical ventilation still allowed for adequate ventilation while, perhaps, avoiding excess lung injury. Based on this principle, high-frequency oscillatory ventilation (HFOV), which provides very small tidal volumes (1 to 2 ml… Read More…

ECMO for Adult ARDS

Posted by Graham McMahon • November 18th, 2011

In the latest article in our Clinical Therapeutics review series, a 41-year-old woman presents with severe pneumonia, and the acute respiratory distress syndrome (ARDS) develops. Despite mechanical ventilation, her oxygenation deteriorates. The use of extracorporeal membrane oxygenation (ECMO) is recommended. ARDS is characterized by the acute onset of hypoxemia and bilateral pulmonary infiltrates consistent with… Read More…

Is Less Really More? Neuromuscular blockers in Early Acute Respiratory Distress Syndrome

Posted by Dominique Bayard • September 15th, 2010

In March of 2010, during an overnight shift in the medical intensive care unit, I was paged to rush to the bedside of a patient being wheeled in with rapidly worsening hypoxemic respiratory failure. The patient was quickly intubated, yet still difficult to oxygenate. The X-ray showed bilateral, patchy infiltrates. Once it was determined these… Read More…