Posts Tagged ‘hepatitis C’

Ledipasvir–Sofosbuvir for Previously Treated HCV

Posted by Carla Rothaus • April 16th, 2014

The old adage, “The more things change, the more they stay the same,” simply does not apply when it comes to the treatment of hepatitis C virus (HCV). The mainstay of HCV treatment for many years has included interferon (peginterferon, since 2001) and ribavirin. While relatively effective for patients with HCV genotypes 2 and 3,… Read More…

HCV-Related Cryoglobulinemic Vasculitis

Posted by Sara Fazio • September 13th, 2013

Cryoglobulins are present in about a quarter of patients with hepatitis C; in some, cryoglobulinemia can become symptomatic or even life-threatening. The latest article in our Current Concepts review series summarizes evolving therapy for the disorder, including new therapeutic options that are becoming available. Cryoglobulins are immunoglobulins characterized by their insolubility at low temperatures and… Read More…

Treatment of Hepatitis C

Posted by Sara Fazio • January 19th, 2012

In a new study of 21 patients with hepatitis C virus genotype 1 infection who had had no response to prior treatment, sustained virologic responses were achieved in 4 of 11 who were treated with two antiviral agents alone and in 9 of 10 who were treated with the antiviral agents plus peginterferon and ribavirin…. Read More…

Hope for Hepatitis C

Posted by John Staples • January 18th, 2012

Imagine, for a moment, that you recently received a brand new Time-O-Matic Time Machine as a gift. How far back would you have to set the dial to see that meaningful progress has been made in the treatment of hepatitis C? First, let’s say you set the dial to January 2011 and –- Puff-kachunk! —… Read More…

Hepatitis C

Posted by Graham McMahon • June 24th, 2011

The latest article in our Clinical Practice series, Chronic Hepatitis C Infection, reviews the evaluation and initial management of chronic hepatitis C infection, with particular attention to the use of new directly acting antiviral agents in treatment regimens. Infection with HCV affects an estimated 180 million people globally. It is a leading cause of chronic… Read More…

A Better Way to Unbind Prometheus? Boceprevir for the Treatment of Chronic Hepatitis C Infection

Posted by John Staples • March 30th, 2011

What do Mickey Mantle, Evel Knievel, and Pamela Anderson have in common? Infamy, certainly, but all three are also reported to have battled chronic hepatitis C virus (HCV) infection. And they aren’t alone: Including a sizable list of celebrities, it is estimated that 160 million people worldwide have the disease, putting them at risk of… Read More…

Management of Incidental Hepatitis C Virus Infection

Posted by Karen Buckley • May 14th, 2009

Our latest Clinical Decisions presents the case of a 25-year-old woman with incidentally identified hepatitis C virus infection. Three possible treatment options, any of which could be considered correct, are provided. We asked you to vote for one and welcomed comments about your choice. A broad selection of these comments are now available for your… Read More…