In our Clinical Problem-Solving series, information about a real patient is presented in stages to an expert clinician, who responds to the information, sharing his or her reasoning with the reader. The latest article, “A Problem in Gestation,” was first presented as an Interactive Medical Case, giving readers the opportunity to test their diagnostic skills…. Read More…
In this week’s Case Record of the Massachusetts General Hospital is a 4-year-old boy was admitted because of a 1-week history of back pain, with sleepiness, constipation, and refusal to walk. The serum calcium level was elevated. Initial radiographs and MRI studies were interpreted as normal. Diagnostic tests were performed. In contrast to adults with… Read More…
A 61-year-old man was admitted with a week-long history of nausea, vomiting, nocturia, and polyuria. During the previous 6 months, he had noted progressive fatigue and a 7-kg (15-lb) weight loss. Read more about this case in our latest Clinical Problem Solving article, In Search of… Mild-to-moderate hypercalcemia (defined as a serum calcium level below… Read More…
Our latest Drug Therapy article, Oral Phosphate Binders in Patients with Kidney Failure, comes from Marcello Tonelli, M.D., Neesh Pannu, M.D., and Braden Manns, M.D. Large observational studies have shown a graded association between levels of serum phosphate and all-cause mortality in patients undergoing dialysis. Several putative mechanisms link elevated serum phosphate levels to… Read More…
