Posts Tagged ‘hypercalcemia’

Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and Neck

Posted by • November 9th, 2016

A 62-year-old man with a history of smoking and excess alcohol use presented with a two-month history of hoarseness and dysphagia and was diagnosed with laryngeal squamous cell carcinoma. Five months after completing concurrent cisplatin and radiation therapy, he returns to his oncologist with lung metastases. He asks about additional therapeutic options for his cancer… Read More…

12-Year-Old Girl with Irritability and Insomnia

Posted by • May 24th, 2013

In the latest Case Record of the Massachusetts General Hospital, a 12-year-old girl with a history of celiac disease, anxiety, and depression was seen in the outpatient psychiatry clinic of this hospital because of irritability, hypersomnia, and multiple somatic symptoms. Psychotherapy and the administration of antidepressants were begun. Pediatric patients with somatization are likely to have… Read More…

Hypercalcemia in Pregnancy

Posted by • September 2nd, 2011

In our Clinical Problem-Solving series, information about a real patient is presented in stages to an expert clinician, who responds to the information, sharing his or her reasoning with the reader.  The latest article, “A Problem in Gestation,” was first presented as an Interactive Medical Case, giving readers the opportunity to test their diagnostic skills. Primary… Read More…

Hypercalcemia in Children

Posted by • February 11th, 2011

In this week’s Case Record of the Massachusetts General Hospital is a 4-year-old boy was admitted because of a 1-week history of back pain, with sleepiness, constipation, and refusal to walk. The serum calcium level was elevated. Initial radiographs and MRI studies were interpreted as normal. Diagnostic tests were performed. In contrast to adults with malignant… Read More…

Hypercalcemia

Posted by • December 3rd, 2010

A 61-year-old man was admitted with a week-long history of nausea, vomiting, nocturia, and polyuria. During the previous 6 months, he had noted progressive fatigue and a 7-kg (15-lb) weight loss.  Read more about this case in our latest Clinical Problem Solving article, In Search of… Mild-to-moderate hypercalcemia (defined as a serum calcium level below 13.5… Read More…

Management of Hyperphosphatemia

Posted by • April 14th, 2010

Our latest Drug Therapy article, Oral Phosphate Binders in Patients with Kidney Failure, comes from Marcello Tonelli, M.D., Neesh Pannu, M.D., and Braden Manns, M.D.    Large observational studies have shown a graded association between levels of serum phosphate and all-cause mortality in patients undergoing dialysis. Several putative mechanisms link elevated serum phosphate levels… Read More…