In the classic tale of Dr. Jekyll and Mr. Hyde, two opposing characters — one a respected gentleman, the other a violent brute — are revealed to be in fact the same person, blurring the lines between good and evil. For patients with leukemia or lymphoma who have undergone bone marrow transplantation, the same could… Read More…
The latest article in our Clinical Practice series provides guidance for care of adult survivors of childhood acute lymphoblastic leukemia, the most common childhood cancer. Treatments are associated with increased late risks of several other conditions; surveillance and patient education strategies are reviewed. There are (as of 2006) an estimated 50,000 survivors of childhood leukemia… Read More…
In a study from Slamon et al., trastuzumab added to a nonanthracycline regimen to treat HER2-positive breast cancer resulted in rates of disease-free and overall survival that were similar to those for an anthracycline-containing regimen, with lower rates of cardiac toxicity and secondary leukemia. The HER2 gene encodes a tyrosine kinase receptor that mediates critical… Read More…
Be sure to watch a striking video on Leukocytosis and Sublingual Microvascular Blood Flow published alongside the study, B-Cell Clones as Early Markers for Chronic Lymphocytic Leukemia. Sidestream dark field (SDF) imaging was used to determine the severity of the leukocytosis. When the patient’s white blood cell count was high, the blood flowed slowly; after… Read More…
