Posts Tagged ‘prostate cancer’

Surgery Versus Watchful Waiting for Localized Prostate Cancer: the 18-Year Debate

Posted by Joshua Allen-Dicker • March 5th, 2014

In 2013, over 238,000 men were diagnosed with prostate cancer in the United States.  Each of these patients and their physicians has undoubtedly been faced with a vexing series of decisions: What should I do next?  Will the treatment help, or will the cure be worse than the disease?  The publication of the 18-year follow-up… Read More…

Urologists’ Use of IMRT for Prostate Cancer

Posted by Sara Fazio • October 25th, 2013

Some urology groups have integrated intensity-modulated radiation therapy (IMRT) into their practice, which allows them to refer patients to their own practice for IMRT. This analysis showed a substantial increase in IMRT use by urologists who acquired ownership of IMRT services. As permitted by the exception for in-office ancillary services in the federal prohibition against… Read More…

Riding Toward Prostate Cancer Prevention

Posted by Rena Xu • August 14th, 2013

Nearly twenty years after the Prostate Cancer Prevention Trial (PCPT) enrolled its first participant, the drama surrounding finasteride use in prostate cancer prevention continues to unfold. Finasteride, a 5-alpha reductase inhibitor, was once touted as a potential public health tool — a means of preventing prostate cancer. Results from the PCPT, a large-scale study that… Read More…

Good to the Bone: Radium-223 Treatment for Metastatic Prostate Cancer

Posted by Rena Xu • July 17th, 2013

Last year, I met a patient with metastatic prostate cancer.  He was in the hospital with severe bone disease, and I was working with a resident involved in his care.  Before we entered the patient’s room, the resident turned to me.  “Remember what you’re about to see,” she said. And I still do. The room… Read More…

Vote Now on PSA Screening

Posted by Karen Buckley • August 16th, 2012

Whether to screen for prostate cancer is an open question for clinicians and patients. Our latest Clinical Decisions presents the case vignette of a 55-year-old man who reports to the primary care clinic for a routine exam and asks whether or not he should have a PSA test. An argument to recommend prostate cancer screening… Read More…

The Prostate Cancer Paradox: Should Prostate Cancer Be Treated?

Posted by Rena Xu • July 18th, 2012

The controversy over prostate cancer screening continues, and more fuel continues to be added to the fire. According to an article published this week in NEJM, not all men with prostate cancer require surgery to treat it. The findings come from the Prostate Cancer Intervention Versus Observation Trial (PIVOT), a study that enrolled 731 patients… Read More…

More Screening Scrutiny: An Update on Screening for Prostate Cancer

Posted by Rena Xu • March 14th, 2012

Last year, the U.S. Preventive Services Task Force (USPSTF) issued a controversial draft recommendation against routine screening for prostate cancer.  The rationale was that for asymptomatic men, prostate-specific antigen (PSA)-based screening offered unclear survival benefit while posing at least a small risk. In this week’s NEJM, an article by Schröder et al. report updated data… Read More…

Screening for Prostate Cancer

Posted by Graham McMahon • November 25th, 2011

In the latest article in our Clinical Practice review series, “Screening for Prostate Cancer,” current recommendations for prostate-specific antigen testing are reviewed, as well as the initial results of two randomized trials. The potential risks of screening, including morbidity from overdiagnosis and overtreatment, are described. In the United States, approximately 90% of prostate cancers are… Read More…

PSA Screening: Discourage or Recommend?

Posted by Karen Buckley • October 27th, 2011

The U.S. Preventive Services Task Force issued a draft recommendation earlier this month that men with no symptoms of prostate cancer should not be screened with the PSA test.  There has been debate about PSA screening for as long as it has existed, and that continues today.  On NEJM.org we have published the views of… Read More…

Androgen Deprivation for Prostate Cancer

Posted by Graham McMahon • July 15th, 2011

In a new study by Jones et al., Radiotherapy and Short-Term Androgen Deprivation for Localized Prostate Cancer, a course of androgen-deprivation therapy before and during radiotherapy prolonged 10-year survival by about 7% among men with intermediate-risk prostate cancer. The risk of erectile dysfunction with the addition of hormone therapy was also about 7% higher. In… Read More…