Posts Tagged ‘type 2 diabetes’

Bardoxolone Methyl in Type 2 Diabetes and Stage 4 Chronic Kidney Disease

Posted by Daniela Lamas • December 26th, 2013

Intuitively, controlling diabetic kidney disease should be easy – manage hyperglycemia, manage blood pressure. And the more control, the better, right? Unfortunately, it hasn’t been so simple. With effective treatment of hyperglycemia and control of blood pressure, the incidence of end-stage renal disease (ESRD) due to diabetes has reached a plateau in the past 10… Read More…

New Clinical Decisions: Controlling Type 2 Diabetes

Posted by Karen Buckley • October 3rd, 2013

Which drug is best for a patient who needs to get her glycated hemoglobin level down to 7.0%? Review the arguments, choose a treatment option, and share your comments in our latest Clinical Decisions. Agnes is a 51-year-old widow with hypertension who has not been able to gain complete control over her type 2 diabetes… Read More…

Insulin and Cardiovascular Outcomes in Dysglycemia

Posted by Sara Fazio • July 27th, 2012

In a new study from the ORIGIN Trial Investigators with a 2-by-2 factorial design, patients with cardiovascular risk factors and dysglycemia or type 2 diabetes received insulin glargine or standard care. Insulin treatment did not affect cardiovascular events, the primary outcome. An elevated fasting plasma glucose level is an independent risk factor for adverse cardiovascular outcomes…. Read More…

Therapy in Youth with Type 2 Diabetes

Posted by Lisa Rosenbaum • June 13th, 2012

Just twenty years ago only 3 of 100 adolescents with diabetes had Type 2 diabetes (T2DM); today that proportion nears 1 in 2. Moreover, this epidemic of T2DM disproportionately affects disadvantaged children, many of whom grow up in environments that lack healthy food options or safe exercise facilities. Though it is clearly urgent to devise medical, behavioral,… Read More…

Medical Therapy vs. Bariatric Surgery in Type 2 Diabetes

Posted by Daniela Lamas • April 27th, 2012

In the 91 years since the discovery of insulin therapy for diabetes by Banting and Best in 1921, the prevalence of type 1 and especially type 2 diabetes has skyrocketed, tied to the ongoing epidemic of obesity. With the global prevalence of type 2 diabetes now expected to hit nearly 10 percent of the world’s… Read More…

Surgery versus Medical Therapy in Obese Diabetics

Posted by Sara Fazio • April 25th, 2012

In a randomized, controlled study of obese patients with type 2 diabetes, those who received medical therapy plus bariatric surgery had significantly better glycemic control at 12 months than did those who received medical therapy alone. The growing incidence of obesity and type 2 diabetes mellitus globally is widely recognized as one of the most challenging contemporary… Read More…

Type 2 Diabetes

Posted by Sara Fazio • April 6th, 2012

The latest article in our Clinical Practice series provides a framework for establishing glycemic targets for patients with type 2 diabetes, taking into account both psychosocial and clinical factors, and discusses strategies to achieve the targets. First-line treatments and additional therapies are discussed. T2DM is the leading cause of blindness, nontraumatic lower-limb amputation, and chronic kidney… Read More…

Panretinal Photocoagulation

Posted by Graham McMahon • October 21st, 2011

In the latest article in our Clinical Therapeutics review series, proliferative retinopathy develops in a 55-year-old man with type 2 diabetes. Panretinal photocoagulation, which causes reduced production of VEGF by destroying hypoxic retinal cells, is recommended. Diminished peripheral and night vision can occur. Data from the Diabetic Retinopathy Study indicate that approximately half of all… Read More…