A 45-year-old health conscious patient who has been with your primary care practice for several years mentions at a regular visit his three relatives with cancers of the breast, ovary, and prostate. He wants to know about genetic testing and any preventive measures he can take.
Do you think he should receive genetic screening? If so, should he be referred for whole-genome sequencing or sequencing of cancer genes only?
Read more about the patient, and arguments for each approach from two experts in the field, in the new Clinical Decisions. Then vote and comment at NEJM.org. Voting is open until July 3.