{"id":10589,"date":"2011-08-01T15:58:44","date_gmt":"2011-08-01T19:58:44","guid":{"rendered":"http:\/\/blogs.nejm.org\/cardioexchange\/?post_type=news&#038;p=10589"},"modified":"2011-08-01T15:58:44","modified_gmt":"2011-08-01T19:58:44","slug":"going-beyond-courage-nhlbi-funds-the-ischemia-study","status":"publish","type":"post","link":"https:\/\/blogs.nejm.org\/cardioexchange\/2011\/08\/01\/going-beyond-courage-nhlbi-funds-the-ischemia-study\/","title":{"rendered":"Going Beyond COURAGE: NHLBI Funds the ISCHEMIA Study"},"content":{"rendered":"<p><a href=\"http:\/\/www.prnewswire.com\/news-releases\/nih-awards-84-million-grant-to-nyu-langone-medical-center-and-partnering-institutions-for-first-of-its-kind-comparative-effectiveness-ischemia-clinical-trial-126510493.html\">The NHLBI has awarded an $84 million grant to fund the International Study of Comparative Health Effectiveness with Medical and Invasive Approaches (ISCHEMIA).<\/a> The trial will randomize 8,000 patients with stable ischemic heart disease and moderate-to-severe ischemia. Two different treatment strategies will be compared:<\/p>\n<ol>\n<li>An invasive strategy, consisting of early routine cardiac catheterization followed by revascularization plus optimal medical therapy (OMT) and lifestyle changes.<\/li>\n<li>A conservative strategy of OMT and lifestyle changes in which invasive procedures will be performed only after failure of OMT.<\/li>\n<\/ol>\n<p>In addition, ISCHEMIA will assess whether the invasive strategy is better able to improve angina-related quality of life.<\/p>\n<p>NYU&#8217;s Judith Hochman is the study chair.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The NHLBI has awarded an $84 million grant to fund the International Study of Comparative Health Effectiveness with Medical and Invasive Approaches (ISCHEMIA). The trial will randomize 8,000 patients with stable ischemic heart disease and moderate-to-severe ischemia. Two different treatment strategies will be compared: An invasive strategy, consisting of early routine cardiac catheterization followed by [&hellip;]<\/p>\n","protected":false},"author":196,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20,9],"tags":[371,931,932,838,827],"class_list":["post-10589","post","type-post","status-publish","format-standard","hentry","category-cardiac-surgery","category-interventional-cardiology","tag-courage","tag-ischemia","tag-nhlbi","tag-optimal-medical-therapy","tag-revascularization"],"_links":{"self":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/10589","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/users\/196"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/comments?post=10589"}],"version-history":[{"count":0,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/10589\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/media?parent=10589"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/categories?post=10589"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/tags?post=10589"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}