{"id":11724,"date":"2011-09-14T10:02:19","date_gmt":"2011-09-14T14:02:19","guid":{"rendered":"http:\/\/blogs.nejm.org\/cardioexchange\/?post_type=news&#038;p=11724"},"modified":"2011-09-14T10:02:19","modified_gmt":"2011-09-14T14:02:19","slug":"study-sheds-light-on-consequences-of-bicuspid-aortic-valve","status":"publish","type":"post","link":"https:\/\/blogs.nejm.org\/cardioexchange\/2011\/09\/14\/study-sheds-light-on-consequences-of-bicuspid-aortic-valve\/","title":{"rendered":"Study Sheds Light on Consequences of Bicuspid Aortic Valve"},"content":{"rendered":"<p>Although bicuspid aortic valve (BAV) is the most frequently occurring congenital heart defect, little is known about the long-term prognosis of people with BAV. Now\u00a0<a href=\"http:\/\/jama.ama-assn.org\/content\/306\/10\/1104.short\">a study published in\u00a0<em>JAMA<\/em><\/a>\u00a0shows that although affected people have a low overall rate of aortic complications, their risk is nevertheless about 8 times greater than the risk of those without BAV.<\/p>\n<p>Hector Michelena and colleagues retrospectively followed 416 BAV patients for 16 years. During that period, two patients had an aortic dissection, representing an incidence of\u00a03.1 cases per 10,000 patient-years &#8212; more than 8 times the risk of the general population. Risk was higher in people 50 years of age or older (17.4 \u00a0cases per 10,000 patient-years) and in people with aortic aneurysms at baseline (44.9 cases per 10,000 patient-years).<\/p>\n<p>At baseline, 384 patients did not have an aneurysm. Some 49 went on to develop an aneurysm, representing an incidence of 84.9 cases per 10,000 patient-years &#8212; 86 times the risk of the general population. Overall, the 25-year rate of aortic surgery was 25%, and the rate of valve replacement was 53%.<\/p>\n<p>The authors write that their findings \u201csupport current recommendations of electively repairing ascending aortic aneurysms and have implications for clinical and echocardiographic surveillance of \u2026 patient subsets.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Although bicuspid aortic valve (BAV) is the most frequently occurring congenital heart defect, little is known about the long-term prognosis of people with BAV. Now\u00a0a study published in\u00a0JAMA\u00a0shows that although affected people have a low overall rate of aortic complications, their risk is nevertheless about 8 times greater than the risk of those without BAV. [&hellip;]<\/p>\n","protected":false},"author":196,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20,1],"tags":[429,978,979],"class_list":["post-11724","post","type-post","status-publish","format-standard","hentry","category-cardiac-surgery","category-general","tag-aortic-valve-stenosis","tag-bicuspid-aortic-valve","tag-congenital-heart-disease"],"_links":{"self":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/11724","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/users\/196"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/comments?post=11724"}],"version-history":[{"count":0,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/11724\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/media?parent=11724"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/categories?post=11724"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/tags?post=11724"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}