{"id":1325,"date":"2009-11-04T17:05:01","date_gmt":"2009-11-04T22:05:01","guid":{"rendered":"http:\/\/blogs.nejm.org\/cardioexchange\/forget-aspirin-in-primary-prevention\/"},"modified":"2011-07-19T17:45:09","modified_gmt":"2011-07-19T21:45:09","slug":"forget-aspirin-in-primary-prevention","status":"publish","type":"post","link":"https:\/\/blogs.nejm.org\/cardioexchange\/2009\/11\/04\/forget-aspirin-in-primary-prevention\/","title":{"rendered":"Forget aspirin in primary prevention?"},"content":{"rendered":"<p>Recent studies (e.g., <a href=\"http:\/\/dtb.bmj.com\/cgi\/content\/abstract\/47\/11\/122\"><em>Drug and Therapeutics Bulletin<\/em> 2009;47:122<\/a>; <a href=\"http:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140-6736%2809%2960503-1\/abstract\"><em>Lancet <\/em>2009; 373:1849<\/a>; <a href=\"http:\/\/www.bmj.com\/cgi\/content\/full\/337\/oct16_2\/a1840?linkType=FULL&amp;journalCode=bmj&amp;resid=337\/oct16_2\/a1840\"><em>BMJ<\/em> 2008; 347:a1840<\/a>) suggest that aspirin confers no benefit whatsoever in primary prevention of cardiovascular disease. The more we explore this issue, the more it appears that only individuals at intermediate or high risk are likely to benefit. We know that <a href=\"http:\/\/www.ahrq.gov\/clinic\/uspstf09\/aspirincvd\/aspcvdart.htm\">data in women<\/a> are weak. <a href=\"http:\/\/www.current-reports.com\/article_frame.cfm?PubID=CR01-2-1-02&amp;Type=Abstract\">Some evidence<\/a> suggests that only those individuals with high hs-CRP levels benefit from aspirin.<\/p>\n<p>How are you making decisions regarding aspirin in primary prevention?<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Recent studies (e.g., Drug and Therapeutics Bulletin 2009;47:122; Lancet 2009; 373:1849; BMJ 2008; 347:a1840) suggest that aspirin confers no benefit whatsoever in primary prevention of cardiovascular disease. The more we explore this issue, the more it appears that only individuals at intermediate or high risk are likely to benefit. We know that data in women [&hellip;]<\/p>\n","protected":false},"author":169,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1325","post","type-post","status-publish","format-standard","hentry","category-general"],"_links":{"self":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/1325","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/users\/169"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/comments?post=1325"}],"version-history":[{"count":0,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/1325\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/media?parent=1325"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/categories?post=1325"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/tags?post=1325"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}