{"id":14178,"date":"2011-11-22T19:38:31","date_gmt":"2011-11-23T00:38:31","guid":{"rendered":"http:\/\/blogs.nejm.org\/cardioexchange\/?post_type=news&p=14178"},"modified":"2011-11-22T19:38:31","modified_gmt":"2011-11-23T00:38:31","slug":"study-examines-role-of-surgery-for-infective-endocarditis-and-heart-failure","status":"publish","type":"post","link":"https:\/\/blogs.nejm.org\/cardioexchange\/2011\/11\/22\/study-examines-role-of-surgery-for-infective-endocarditis-and-heart-failure\/","title":{"rendered":"Study Examines Role of Surgery for Infective Endocarditis and Heart Failure"},"content":{"rendered":"

Although current guidelines recommend valve surgery for\u00a0patients with infective endocarditis and heart failure (HF), a\u00a0large prospective registry finds that many of these patients do not undergo surgery — and have much worse outcomes.<\/p>\n

In a paper published in\u00a0JAMA<\/em><\/a>, Todd Kiefer and colleagues report on 4166 patients with infective endocarditis enrolled in the International Collaboration on Endocarditis – Prospective Cohort Study. One third of the patients had HF, yet only 61.7% of these had valve surgery. In-hospital mortality was 29.7% for all patients with HF, but it was significantly lower in the surgical group than in the medical therapy group: 20.6% versus 44.8% (p<0.001). At 1 year, the difference in mortality was larger: 29.1% versus 58.4% (p<0.001). The investigators report that the association between surgery and survival “was apparent across the spectrum of HF severity.”<\/p>\n

The authors write that their results support the need for “multidisciplinary, guideline-based management of infective endocarditis.”<\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Although current guidelines recommend valve surgery for\u00a0patients with infective endocarditis and heart failure (HF), a\u00a0large prospective registry finds that many of these patients do not undergo surgery — and have much worse outcomes. In a paper published in\u00a0JAMA, Todd Kiefer and colleagues report on 4166 patients with infective endocarditis enrolled in the International Collaboration on […]<\/p>\n","protected":false},"author":196,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20,14],"tags":[1050,1051],"class_list":["post-14178","post","type-post","status-publish","format-standard","hentry","category-cardiac-surgery","category-heart-failure","tag-infective-endocarditis","tag-valve-surgery"],"_links":{"self":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/14178","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/users\/196"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/comments?post=14178"}],"version-history":[{"count":0,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/14178\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/media?parent=14178"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/categories?post=14178"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/tags?post=14178"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}