{"id":1427,"date":"2010-02-09T17:50:36","date_gmt":"2010-02-09T22:50:36","guid":{"rendered":"http:\/\/blogs.nejm.org\/cardioexchange\/an-endeavor-to-compare-2nd-generationdes\/"},"modified":"2011-07-19T17:44:18","modified_gmt":"2011-07-19T21:44:18","slug":"an-endeavor-to-compare-2nd-generationdes","status":"publish","type":"post","link":"https:\/\/blogs.nejm.org\/cardioexchange\/2010\/02\/09\/an-endeavor-to-compare-2nd-generationdes\/","title":{"rendered":"An ENDEAVOR to COMPARE 2nd Generation\u00a0DES"},"content":{"rendered":"<p>In two recent studies, second-generation drug-eluting stents were compared with first-generation paclitaxel-eluting stents.&nbsp; In <a href=\"http:\/\/www.sciencedirect.com\/science?_ob=ArticleURL&amp;_udi=B6T1B-4Y3YG2D-1&amp;_user=108488&amp;_coverDate=01%2F22%2F2010&amp;_rdoc=1&amp;_fmt=high&amp;_orig=search&amp;_sort=d&amp;_docanchor=&amp;view=c&amp;_acct=C000059724&amp;_version=1&amp;_urlVersion=0&amp;_userid=108488&amp;md5=57daf20f6ab71f245d212c9aca7689e0\">COMPARE<\/a>, the everolimus-eluting stent was superior (31% risk reduction in \u201ctarget lesion failure\u201d), whereas in <a href=\"http:\/\/interventions.onlinejacc.org\/cgi\/content\/abstract\/2\/12\/1208\">ENDEAVOR IV<\/a>, the zotarolimus-eluting stent showed similar efficacy and safety to the paclitaxel-eluting stent. &nbsp;In light of these data, is there any role for the zotarolimus-eluting stent?&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In two recent studies, second-generation drug-eluting stents were compared with first-generation paclitaxel-eluting stents.&nbsp; In COMPARE, the everolimus-eluting stent was superior (31% risk reduction in \u201ctarget lesion failure\u201d), whereas in ENDEAVOR IV, the zotarolimus-eluting stent showed similar efficacy and safety to the paclitaxel-eluting stent. &nbsp;In light of these data, is there any role for the zotarolimus-eluting [&hellip;]<\/p>\n","protected":false},"author":190,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1,9],"tags":[],"class_list":["post-1427","post","type-post","status-publish","format-standard","hentry","category-general","category-interventional-cardiology"],"_links":{"self":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/1427","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/users\/190"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/comments?post=1427"}],"version-history":[{"count":0,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/1427\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/media?parent=1427"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/categories?post=1427"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/tags?post=1427"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}