{"id":1484,"date":"2010-03-29T19:14:37","date_gmt":"2010-03-29T23:14:37","guid":{"rendered":"http:\/\/blogs.nejm.org\/cardioexchange\/%e2%80%a2-screening-for-type-2-diabetes%e2%80%a2-fda-cracks-down-on-unapproved-nitroglycerin\/"},"modified":"2011-07-19T17:45:00","modified_gmt":"2011-07-19T21:45:00","slug":"%e2%80%a2-screening-for-type-2-diabetes%e2%80%a2-fda-cracks-down-on-unapproved-nitroglycerin","status":"publish","type":"post","link":"https:\/\/blogs.nejm.org\/cardioexchange\/2010\/03\/29\/%e2%80%a2-screening-for-type-2-diabetes%e2%80%a2-fda-cracks-down-on-unapproved-nitroglycerin\/","title":{"rendered":"\u2022 Screening for Type 2 Diabetes<br \/>\u2022 FDA Cracks Down on Unapproved Nitroglycerin"},"content":{"rendered":"<p><strong>Screening for Type 2 Diabetes<\/strong>:\u00a0Kahn et al. used a sophisticated computer model to assess the impact of 8 different screening strategies to detect type 2 diabetes in the US. The researchers concluded that screening is\u00a0cost effective when started between the ages of 30 and 45 years of age, with screening repeated every 3\u20135 years. The study appears online in <em><a href=\"http:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140-6736%2809%2962162-0\/abstract\">the Lancet<\/a><\/em>. In an <a href=\"http:\/\/www.thelancet.com\/journals\/lancet\/article\/PIIS0140-6736%2810%2960455-2\/fulltext\">accompanying comment<\/a>,\u00a0Guy Rutten write that the study &#8220;provides further evidence that screening for diabetes should be combined with screening for hypertension and lipid tests.&#8221; <\/p>\n<p><strong>FDA Cracks Down on Unapproved Nitroglycerin<\/strong>:\u00a0Last week <a href=\"http:\/\/www.fda.gov\/Drugs\/GuidanceComplianceRegulatoryInformation\/EnforcementActivitiesbyFDA\/SelectedEnforcementActionsonUnapprovedDrugs\/ucm204351.htm\">the FDA<\/a> ordered\u00a0two companies\u00a0to stop selling unapproved nitroglycerin tablets. <a href=\"http:\/\/www.nytimes.com\/2010\/03\/27\/business\/27nitro.html?scp=1&amp;sq=nitroglycerin&amp;st=cse\">A <em>New York Times<\/em> story <\/a>over the weekend explored the larger dimension of the story, pointing out that only one nitroglycerin tablet, Pfizer&#8217;s Nitrostat, has undergone the FDA approval process, and that 80% of the nitroglycerin used in the US has never been subject to regulatory scrutiny. The Times story quotes\u00a0Harry Lever, a cardiologist at the Cleveland Clinic:\u00a0\u201cIf it\u2019s not approved and no one has tested it, we can\u2019t be sure that it\u2019s safe and effective.\u201d <\/p>\n","protected":false},"excerpt":{"rendered":"<p>Screening for Type 2 Diabetes:\u00a0Kahn et al. used a sophisticated computer model to assess the impact of 8 different screening strategies to detect type 2 diabetes in the US. The researchers concluded that screening is\u00a0cost effective when started between the ages of 30 and 45 years of age, with screening repeated every 3\u20135 years. The [&hellip;]<\/p>\n","protected":false},"author":196,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1484","post","type-post","status-publish","format-standard","hentry","category-general"],"_links":{"self":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/1484","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/users\/196"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/comments?post=1484"}],"version-history":[{"count":0,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/1484\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/media?parent=1484"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/categories?post=1484"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/tags?post=1484"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}