{"id":1554,"date":"2010-06-10T17:05:46","date_gmt":"2010-06-10T21:05:46","guid":{"rendered":"http:\/\/blogs.nejm.org\/cardioexchange\/%e2%80%a2cardiac-embolism-may-have-killed-13th-century-mummy%e2%80%a2fda-panels-to-review-rosiglitazone-and-dabigatran\/"},"modified":"2011-07-19T17:44:57","modified_gmt":"2011-07-19T21:44:57","slug":"%e2%80%a2cardiac-embolism-may-have-killed-13th-century-mummy%e2%80%a2fda-panels-to-review-rosiglitazone-and-dabigatran","status":"publish","type":"post","link":"https:\/\/blogs.nejm.org\/cardioexchange\/2010\/06\/10\/%e2%80%a2cardiac-embolism-may-have-killed-13th-century-mummy%e2%80%a2fda-panels-to-review-rosiglitazone-and-dabigatran\/","title":{"rendered":"\u2022Cardiac Embolism May Have Killed 13th Century Mummy<br \/>\u2022FDA Panels to Review Rosiglitazone and Dabigatran"},"content":{"rendered":"<p><strong>Cardiac Embolism May Have Killed 13th Century Mummy: <\/strong>Italian researchers may have solved a 700-year-old medical mystery. It had previously been speculated that tuberculosis had been the cause of death of an 18- to 19-year-old girl who died in the 13th century and whose mummified remains have been preserved at the Santa Rosa monastery in Italy. But Ruggero D&#8217;Anastasio and colleagues found no evidence of chronic infectious disease. Instead, examination of the mummified chest and heart is consistent with Cantrell&#8217;s syndrome, and radiographic evidence of a mass between the apex of the left ventricle and the entry of the diverticulum suggests that the girl may have died of a cardiac embolism. The article appears in <a href=\"http:\/\/www.lancet.com\/journals\/lancet\/article\/PIIS0140-6736%2809%2960729-7\/fulltext\">the <em>Lancet<\/em><\/a>.<br \/>\n<strong><br \/>\nBusy Summer at the FDA: <\/strong>In addition to <a href=\"http:\/\/cardioexchange.org\/blogPost?postId=697\">the previously announced FDA advisory panel<\/a> for the ticagrelor&nbsp;(Brilanta, AstraZeneca)&nbsp;NDA on July 28, the FDA will hold <a href=\"http:\/\/www.fda.gov\/AdvisoryCommittees\/Calendar\/ucm214612.htm\">an extraordinary 2-day advisory panel<\/a> to consider the fate of rosiglitazone (Avandia) on July 13 and 14. In addition, <a href=\"http:\/\/www.theheart.org\/article\/1086745.do\">heart<em>wire<\/em> reports<\/a>, but the FDA has not yet officially announced, that dabigatran&nbsp;(Pradax, Boehringer Ingelheim) will be reviewed on September 17. The FDA normally posts a detailed agenda, briefing materials, and the panel roster two days prior to the meeting.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Cardiac Embolism May Have Killed 13th Century Mummy: Italian researchers may have solved a 700-year-old medical mystery. It had previously been speculated that tuberculosis had been the cause of death of an 18- to 19-year-old girl who died in the 13th century and whose mummified remains have been preserved at the Santa Rosa monastery in [&hellip;]<\/p>\n","protected":false},"author":196,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1554","post","type-post","status-publish","format-standard","hentry","category-general"],"_links":{"self":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/1554","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/users\/196"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/comments?post=1554"}],"version-history":[{"count":0,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/1554\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/media?parent=1554"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/categories?post=1554"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/tags?post=1554"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}