{"id":1555,"date":"2010-06-11T13:33:44","date_gmt":"2010-06-11T17:33:44","guid":{"rendered":"http:\/\/blogs.nejm.org\/cardioexchange\/%e2%80%a2fda-announces-ongoing-safety-review-of-olmesartan\/"},"modified":"2011-07-19T17:44:57","modified_gmt":"2011-07-19T21:44:57","slug":"fda-announces-ongoing-safety-review-of-olmesartan","status":"publish","type":"post","link":"https:\/\/blogs.nejm.org\/cardioexchange\/2010\/06\/11\/fda-announces-ongoing-safety-review-of-olmesartan\/","title":{"rendered":"FDA Announces Ongoing Safety Review of Olmesartan"},"content":{"rendered":"<p><a href=\"http:\/\/www.fda.gov\/Drugs\/DrugSafety\/PostmarketDrugSafetyInformationforPatientsandProviders\/ucm215222.htm\">The FDA announced an ongoing safety review of olmesartan (Benicar).<\/a> The agency said it &#8220;has not concluded that Benicar increases the risk of death\u201d and advises patients and healthcare professionals that it &#8220;currently believes that the benefits of Benicar in patients with high blood pressure continue to outweigh its potential risks.&#8221; The review was prompted by unexpected findings in the <a href=\"http:\/\/clinicaltrials.gov\/ct2\/show\/NCT00185159?term=roadmap+olmesartan&amp;rank=1\">ROADMAP<\/a> and <a href=\"http:\/\/clinicaltrials.gov\/ct2\/show\/study\/NCT00141453\">ORIENT<\/a>&nbsp;clinical trials of an increased number of cardiovascular deaths in patients taking olmesartan compared to placebo.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The FDA announced an ongoing safety review of olmesartan (Benicar). The agency said it &#8220;has not concluded that Benicar increases the risk of death\u201d and advises patients and healthcare professionals that it &#8220;currently believes that the benefits of Benicar in patients with high blood pressure continue to outweigh its potential risks.&#8221; The review was prompted [&hellip;]<\/p>\n","protected":false},"author":196,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1555","post","type-post","status-publish","format-standard","hentry","category-general"],"_links":{"self":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/1555","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/users\/196"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/comments?post=1555"}],"version-history":[{"count":0,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/1555\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/media?parent=1555"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/categories?post=1555"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/tags?post=1555"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}