{"id":15717,"date":"2012-01-30T14:59:25","date_gmt":"2012-01-30T19:59:25","guid":{"rendered":"http:\/\/blogs.nejm.org\/cardioexchange\/?post_type=news&#038;p=15717"},"modified":"2012-01-30T14:59:25","modified_gmt":"2012-01-30T19:59:25","slug":"very-large-observational-study-finds-significant-mortality-advantage-for-cabg-over-pci-in-high-risk-patients","status":"publish","type":"post","link":"https:\/\/blogs.nejm.org\/cardioexchange\/2012\/01\/30\/very-large-observational-study-finds-significant-mortality-advantage-for-cabg-over-pci-in-high-risk-patients\/","title":{"rendered":"Very Large Observational Study Finds Significant Mortality Advantage for CABG Over PCI in High-Risk Patients"},"content":{"rendered":"<p>Although PCI has a small, early mortality benefit compared to CABG in high-risk patients, after the first year a striking survival advantage for CABG develops, according to results of the ASCERT study, presented on Monday at\u00a0<a href=\"http:\/\/www.sts.org\/education-meetings\/sts-annual-meeting\">the annual meeting of the Society of Thoracic Surgeons (STS).<\/a><\/p>\n<p>Fred Edwards presented the high-risk subset of ASCERT (ACCF-STS Database Collaboration on the Comparative Effectiveness of Revascularization Strategies), an NHLBI-funded study based on linked data from the STS, the ACC, and CMS. (The full results of ASCERT will be presented in March at the ACC scientific sessions.) The study population\u00a0included patients 65 or older with 2- or 3-vessel disease who underwent CABG or PCI from 2004 through 2007. Some 189,793 patients were followed in the study; 103,549 underwent PCI and 86,244 underwent CABG.<\/p>\n<p>At 4 years, there was a 22% risk reduction in adjusted mortality in the CABG group compared to the PCI group (RR, 0.78; CI, 0.74-0.82). A similar pattern was observed in patients regardless of age, sex, diabetes status, and ejection fraction.<\/p>\n<p>&#8220;Previous observational studies have shown a long-term survival advantage for CABG over PCI. These partial ASCERT results confirm that in important high-risk clinical subsets the CABG survival advantage can also be seen in a large nationwide population,&#8221; said Edwards in an STS press release.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Although PCI has a small, early mortality benefit compared to CABG in high-risk patients, after the first year a striking survival advantage for CABG develops, according to results of the ASCERT study, presented on Monday at\u00a0the annual meeting of the Society of Thoracic Surgeons (STS). Fred Edwards presented the high-risk subset of ASCERT (ACCF-STS Database [&hellip;]<\/p>\n","protected":false},"author":196,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[20,1,9],"tags":[231,233,301,827],"class_list":["post-15717","post","type-post","status-publish","format-standard","hentry","category-cardiac-surgery","category-general","category-interventional-cardiology","tag-cabg","tag-outcomes","tag-pci","tag-revascularization"],"_links":{"self":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/15717","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/users\/196"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/comments?post=15717"}],"version-history":[{"count":0,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/15717\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/media?parent=15717"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/categories?post=15717"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/tags?post=15717"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}