{"id":2489,"date":"2010-08-10T15:16:41","date_gmt":"2010-08-10T19:16:41","guid":{"rendered":"http:\/\/blogs.nejm.org\/cardioexchange\/?p=2489"},"modified":"2011-07-19T17:44:54","modified_gmt":"2011-07-19T21:44:54","slug":"allopurinol-in-gout-and-heart-failure","status":"publish","type":"post","link":"https:\/\/blogs.nejm.org\/cardioexchange\/2010\/08\/10\/allopurinol-in-gout-and-heart-failure\/","title":{"rendered":"Allopurinol in Gout and Heart Failure"},"content":{"rendered":"<p>Thanassoulis and colleagues analyzed data from\u00a025,000 Canadian heart failure (HF) patients in <a href=\"http:\/\/archinte.ama-assn.org\/cgi\/content\/full\/170\/15\/1358\">a paper appearing in <\/a><em><a href=\"http:\/\/archinte.ama-assn.org\/cgi\/content\/full\/170\/15\/1358\">Archives of Internal Medicine<\/a><\/em>. They found that patients with a recent or remote history of gout were at high risk for HF readmission or death. Although there was no significant association between allopurinol use in the overall study population, among patients with a history of gout, allopurinol use was associated with a significant reduction in HF events. The authors conclude that &#8220;given the limited novel treatment options available for HF patients, allopurinol may be an important therapeutic consideration in certain subgroups of patients with HF.&#8221;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Thanassoulis and colleagues analyzed data from\u00a025,000 Canadian heart failure (HF) patients in a paper appearing in Archives of Internal Medicine. They found that patients with a recent or remote history of gout were at high risk for HF readmission or death. Although there was no significant association between allopurinol use in the overall study population, [&hellip;]<\/p>\n","protected":false},"author":196,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[14],"tags":[289,288,287],"class_list":["post-2489","post","type-post","status-publish","format-standard","hentry","category-heart-failure","tag-allopurinol","tag-gout","tag-heart-failure-2"],"_links":{"self":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/2489","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/users\/196"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/comments?post=2489"}],"version-history":[{"count":0,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/2489\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/media?parent=2489"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/categories?post=2489"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/tags?post=2489"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}