{"id":2696,"date":"2010-08-24T14:55:08","date_gmt":"2010-08-24T18:55:08","guid":{"rendered":"http:\/\/blogs.nejm.org\/cardioexchange\/?p=2696"},"modified":"2011-07-19T17:44:53","modified_gmt":"2011-07-19T21:44:53","slug":"study-suggests-prognostic-power-of-dyspnea-in-acute-heart-failure","status":"publish","type":"post","link":"https:\/\/blogs.nejm.org\/cardioexchange\/2010\/08\/24\/study-suggests-prognostic-power-of-dyspnea-in-acute-heart-failure\/","title":{"rendered":"Study Suggests Prognostic Power of Dyspnea in Acute Heart Failure"},"content":{"rendered":"<p>Results of a study with the hormone relaxin suggest that a lack of ongoing dyspnea relief may be an important predictor of outcome. Marco Metra and fellow investigators in the Pre-RELAX-AHF study randomized 232 patients with acute heart failure to placebo or one of 4 doses of relaxin. Only 25% of all patients in the study achieved early dyspnea relief, and patients who lacked persistent dyspnea relief and who had worsening heart failure had a longer length of initial hospital stay and a worse outcome at 60 days. The findings, conclude the authors in their<a href=\"http:\/\/eurjhf.oxfordjournals.org\/content\/early\/2010\/08\/19\/eurjhf.hfq132.abstract?sid=1d1187c6-ccdd-4751-be97-b0ab29731d11\"> report in the <em>European Journal of Heart Failure<\/em><\/a>, suggest that &#8220;beyond being the main measure&#8221; of acute heart failure symptoms, dyspnea endpoints &#8220;are also related to prognosis and hence may be regarded as important and meaningful targets of therapy.&#8221;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Results of a study with the hormone relaxin suggest that a lack of ongoing dyspnea relief may be an important predictor of outcome. Marco Metra and fellow investigators in the Pre-RELAX-AHF study randomized 232 patients with acute heart failure to placebo or one of 4 doses of relaxin. Only 25% of all patients in the [&hellip;]<\/p>\n","protected":false},"author":196,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1,14],"tags":[322,287,321],"class_list":["post-2696","post","type-post","status-publish","format-standard","hentry","category-general","category-heart-failure","tag-dyspnea","tag-heart-failure-2","tag-relaxin"],"_links":{"self":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/2696","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/users\/196"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/comments?post=2696"}],"version-history":[{"count":0,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/2696\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/media?parent=2696"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/categories?post=2696"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/tags?post=2696"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}