{"id":2790,"date":"2010-08-30T16:15:27","date_gmt":"2010-08-30T20:15:27","guid":{"rendered":"http:\/\/blogs.nejm.org\/cardioexchange\/?p=2790"},"modified":"2011-07-19T17:44:52","modified_gmt":"2011-07-19T21:44:52","slug":"study-finds-african-americans-at-increased-risk-for-stent-thrombosis","status":"publish","type":"post","link":"https:\/\/blogs.nejm.org\/cardioexchange\/2010\/08\/30\/study-finds-african-americans-at-increased-risk-for-stent-thrombosis\/","title":{"rendered":"Study Finds African-Americans at Increased Risk for Stent Thrombosis"},"content":{"rendered":"<p>African-Americans are nearly three times more likely than other races to develop stent thrombosis after receiving a drug-eluting stent, according to <a href=\"http:\/\/circ.ahajournals.org\/cgi\/content\/abstract\/CIRCULATIONAHA.109.907998v1\">a new study appearing in <em>Circulation<\/em><\/a>. Ron Waksman and colleagues analyzed data from a large, single-center registry of 7,236 patients who received a DES and found that African-American race was the single strongest predictor of late stent thrombosis \u2014 even after accounting for other known risk factors, and even though African-Americans were more likely to comply with their prescriptions for antiplatelet therapy. The rates of stent thrombosis for African-Americans, compared with non-African-Americans, were:<\/p>\n<ul>\n<li>1.71% vs. 0.59% at 30 days;<\/li>\n<li>2.25% vs. 0.79% at 1 year;<\/li>\n<li>2.78% vs. 1.09% at 2 years;<\/li>\n<li>3.67% vs. 1.25% at 3 years.<\/li>\n<\/ul>\n<p>Overall mortality at 3 years was also higher among African-Americans: 24.9% versus 13.1% for other races.<\/p>\n<p>In the discussion section, the authors write: &#8220;Because the traditional socioeconomic factors that plague racial disparities in health care have been accounted for in our study, further mechanisms such as genetic differences by which black race predicts ST [stent thrombosis] must be pursued.&#8221;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>African-Americans are nearly three times more likely than other races to develop stent thrombosis after receiving a drug-eluting stent, according to a new study appearing in Circulation. Ron Waksman and colleagues analyzed data from a large, single-center registry of 7,236 patients who received a DES and found that African-American race was the single strongest predictor [&hellip;]<\/p>\n","protected":false},"author":196,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[9],"tags":[330,331,332],"class_list":["post-2790","post","type-post","status-publish","format-standard","hentry","category-interventional-cardiology","tag-african-americans","tag-des","tag-stent-thrombosis"],"_links":{"self":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/2790","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/users\/196"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/comments?post=2790"}],"version-history":[{"count":0,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/2790\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/media?parent=2790"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/categories?post=2790"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/tags?post=2790"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}