{"id":30362,"date":"2012-07-10T10:14:08","date_gmt":"2012-07-10T14:14:08","guid":{"rendered":"http:\/\/blogs.nejm.org\/cardioexchange\/?post_type=news&#038;p=30362"},"modified":"2012-07-10T10:14:08","modified_gmt":"2012-07-10T14:14:08","slug":"intensive-insulin-therapies-similarly-efficacious-in-diabetes","status":"publish","type":"post","link":"https:\/\/blogs.nejm.org\/cardioexchange\/2012\/07\/10\/intensive-insulin-therapies-similarly-efficacious-in-diabetes\/","title":{"rendered":"Intensive Insulin Therapies Similarly Efficacious in Diabetes"},"content":{"rendered":"<p>Multiple daily insulin injections and continuous subcutaneous insulin analogue infusion are similarly effective in lowering hemoglobin A1c levels while limiting episodes of severe hypoglycemia in type 2 diabetes, according to a <a href=\"http:\/\/annals.org\/article.aspx?articleid=1215793\">systematic review<\/a> published in the<em> Annals of Internal Medicine<\/em>.<\/p>\n<p>The analysis included 33 randomized controlled trials among children and adults with type 1 or type 2 diabetes. Among the other findings:<\/p>\n<ul>\n<li>The two intensive therapies also performed similarly well in children with type 1 diabetes; in adults with type 1 diabetes, however, continuous subcutaneous infusion led to greater HbA1c reductions than did multiple daily injections (this latter outcome was heavily influenced by one trial).<\/li>\n<li>Real-time continuous blood glucose monitoring, assessed in type 1 diabetes, generally produced better outcomes than self-monitoring of blood glucose with fingersticks.<\/li>\n<\/ul>\n<p>The authors caution that most of the studies in their analysis were of fair to poor quality \u2014 with the largest having 322 participants.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Multiple daily insulin injections and continuous subcutaneous insulin analogue infusion are similarly effective in lowering hemoglobin A1c levels while limiting episodes of severe hypoglycemia in type 2 diabetes, according to a systematic review published in the Annals of Internal Medicine. The analysis included 33 randomized controlled trials among children and adults with type 1 or [&hellip;]<\/p>\n","protected":false},"author":577,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-30362","post","type-post","status-publish","format-standard","hentry","category-general"],"_links":{"self":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/30362","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/users\/577"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/comments?post=30362"}],"version-history":[{"count":0,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/30362\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/media?parent=30362"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/categories?post=30362"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/tags?post=30362"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}