{"id":3191,"date":"2010-09-13T15:07:58","date_gmt":"2010-09-13T19:07:58","guid":{"rendered":"http:\/\/blogs.nejm.org\/cardioexchange\/?p=3191"},"modified":"2011-07-19T17:44:16","modified_gmt":"2011-07-19T21:44:16","slug":"three-year-syntax-results-sensible-not-sensational","status":"publish","type":"post","link":"https:\/\/blogs.nejm.org\/cardioexchange\/2010\/09\/13\/three-year-syntax-results-sensible-not-sensational\/","title":{"rendered":"Three-year SYNTAX Results: Sensible, Not Sensational"},"content":{"rendered":"<p>In SYNTAX, 1800 patients with multivessel and\/or left main disease were randomized to CABG or PCI with DES after a surgeon and an interventional cardiologist reviewed the coronary angiogram and agreed that either procedure was appropriate. (See the <a href=\"http:\/\/blogs.nejm.org\/cardioexchange\/syntax-at-3-years-cabg-still-winning-but-pci-acceptable-in-low-risk-patients\/\">CardioExchange News blog <\/a>for more study information.)<\/p>\n<p><strong><em>The SYNTAX 3-year results show that patients with a low SYNTAX score have similar outcomes with PCI or CABG, whereas those with an intermediate or high score have a better outcome with CABG.<\/em><\/strong><\/p>\n<p>1) In the cohort as a whole, MACCE rates were higher for PCI than for CABG (28% vs 20%), mainly\u00a0because of\u00a0a higher rate of repeat revascularization in the PCI group.<\/p>\n<p style=\"padding-left: 30px;\">a) Composite safety (death\/stroke\/MI) was similar\u00a0in the\u00a0PCI and CABG groups (14.1% and 12.0%, respectively)<\/p>\n<p style=\"padding-left: 30px;\">b) MI incidence was nearly twice as high in PCI patients than in CABG patients (7.1% vs. 3.6%)<\/p>\n<p>2)\u00a0In patients with a low (0-22) SYNTAX score, MACCE rates were similar for PCI and CABG (22.7% and 22.5%, respectively)<\/p>\n<p>3)\u00a0In patients with an intermediate (23-32) or a high SYNTAX score, MACCE rates were higher with PCI than CABG (27.4% vs 18.9% for an intermediate score; 34.1% vs 19.5% for a high score)<\/p>\n<p><strong><em>Now be honest&#8230;.do you calculate a SYNTAX score for your patients?<\/em><\/strong><\/p>\n<p><strong><em>If you don&#8217;t, how do you\u00a0determine which patients will do as well with PCI as with CABG?<\/em><\/strong><\/p>\n","protected":false},"excerpt":{"rendered":"<p>In SYNTAX, 1800 patients with multivessel and\/or left main disease were randomized to CABG or PCI with DES after a surgeon and an interventional cardiologist reviewed the coronary angiogram and agreed that either procedure was appropriate. (See the CardioExchange News blog for more study information.) The SYNTAX 3-year results show that patients with a low [&hellip;]<\/p>\n","protected":false},"author":214,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1,9],"tags":[231,301,373,391],"class_list":["post-3191","post","type-post","status-publish","format-standard","hentry","category-general","category-interventional-cardiology","tag-cabg","tag-pci","tag-stable-angina","tag-syntax"],"_links":{"self":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/3191","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/users\/214"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/comments?post=3191"}],"version-history":[{"count":0,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/3191\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/media?parent=3191"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/categories?post=3191"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/tags?post=3191"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}