{"id":32741,"date":"2012-11-05T12:53:47","date_gmt":"2012-11-05T17:53:47","guid":{"rendered":"http:\/\/blogs.nejm.org\/cardioexchange\/?post_type=voices&p=32741"},"modified":"2012-11-05T12:54:21","modified_gmt":"2012-11-05T17:54:21","slug":"selections-from-richard-lehmans-literature-review-november-5th","status":"publish","type":"post","link":"https:\/\/blogs.nejm.org\/cardioexchange\/2012\/11\/05\/selections-from-richard-lehmans-literature-review-november-5th\/","title":{"rendered":"Selections from Richard Lehman\u2019s Literature Review: November 5th"},"content":{"rendered":"

CardioExchange is pleased to reprint selections from Dr. Richard Lehman\u2019s\u00a0weekly journal review blog<\/a>\u00a0at\u00a0BMJ.com<\/a>. Selected summaries are relevant to our audience, but we encourage members to engage with the\u00a0entire blog<\/a>.<\/em><\/p>\n

BMJ 3 Nov 2012 Vol 345<\/strong><\/p>\n

Fish Consumption, Omega-3 Fatty-Acids, and Cerebrovascular Disease:<\/strong> Yes, Jeeves was right: fish is good for the brain. I have told you this before: here is a systematic review<\/a> of the protection afforded by fish consumption against the risk of cerebrovascular disease. It\u2019s not just the oils: \u201cthe beneficial effect of fish intake on cerebrovascular risk is likely to be mediated through the interplay of a wide range of nutrients abundant in fish.\u201d But actually I couldn\u2019t give a hoot: \u201cdietary science\u201d is just a mess of confounders: I eat fish because I like fish.<\/p>\n

HRT and Cardiovascular Events in Recently Post-Menopausal Women:<\/strong> This week sees the print version of the now-famous Danish randomized trial<\/a> of hormone replacement therapy that contradicts the Women\u2019s Health Initiative and shows a cardiovascular protective effect from the early use of HRT. I will leave it to others to discuss the timing hypothesis and so forth. What we need are some good decision aids for women. I nearly said \u201cpatients\u201d \u2013 but why should taking HRT turn people into patients? Why should doctors in fact have anything to do with an informed woman\u2019s decision about using HRT for postmenopausal symptoms?<\/p>\n

<\/strong>Using a Meta-Analysis of Coronary CT Angiography Studies<\/strong> to Assess Diagnostic Tests with a 3×2 Table:<\/strong> All doctors need to become competent diagnosticians. Yet most that I have encountered find it difficult even to use a two-by-two table to assess diagnostic tests. This is not going to change. This important article, based on a meta-analysis of coronary CT angiography studies, urges the adoption of 3 by 2 tables, with an intermediate category of \u201cnon-evaluable\u201d. I believe the authors are right: and I believe also that once we have made this move forward, we then have to find ways of making it intuitive and practical for jobbing clinicians.<\/p>\n","protected":false},"excerpt":{"rendered":"

This week’s topics include fish consumption, omega-3 fatty acids, and cerebrovascular disease; HRT and cardiovascular disease in recently menopausal women; and more.<\/p>\n","protected":false},"author":475,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[1550,1000,1549,1501,1214,1100],"class_list":["post-32741","post","type-post","status-publish","format-standard","hentry","category-general","tag-cerebrovascular-disease","tag-diagnostic-testing","tag-fish-consumption","tag-hrt","tag-omega-3-fatty-acids","tag-postmenopausal-women"],"_links":{"self":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/32741","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/users\/475"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/comments?post=32741"}],"version-history":[{"count":0,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/32741\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/media?parent=32741"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/categories?post=32741"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/tags?post=32741"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}