{"id":38189,"date":"2013-08-28T11:46:32","date_gmt":"2013-08-28T15:46:32","guid":{"rendered":"http:\/\/blogs.nejm.org\/cardioexchange\/?post_type=news&#038;p=38189"},"modified":"2013-08-28T11:46:32","modified_gmt":"2013-08-28T15:46:32","slug":"american-heart-association-announces-late-breaking-clinical-trials","status":"publish","type":"post","link":"https:\/\/blogs.nejm.org\/cardioexchange\/2013\/08\/28\/american-heart-association-announces-late-breaking-clinical-trials\/","title":{"rendered":"American Heart Association Announces Late-Breaking Clinical Trials"},"content":{"rendered":"<p>There are still a few days left in August, and the European Society of Cardiology meeting doesn&#8217;t start until this weekend in Amsterdam. Nevertheless, the\u00a0American Heart Association\u00a0has released the list of late-breaking clinical trials for its annual meeting in November.<\/p>\n<p><strong>Late-Breaking Clinical Trials 1:\u00a0Acute Cardiovascular and Cerebrovascular Care<\/strong><\/p>\n<ul>\n<li><em>Sunday, Nov 17, 2013, 4:00 PM &#8211; 5:19 PM<\/em><\/li>\n<\/ul>\n<p>Moderators:<\/p>\n<ul>\n<li>Lance Becker, Philadelphia, PA<\/li>\n<li>Stephen Bernard, Melbourne, Australia<\/li>\n<\/ul>\n<p>4:00 PM:\u00a0<strong>Nitrites in Acute Myocardial Infarction<\/strong><\/p>\n<ul>\n<li>Nishat Siddiqi, Univ of Aberdeen, Aberdeen, United Kingdom<\/li>\n<li>Discussant:\u00a0Kenneth Bloch, Boston, MA<\/li>\n<\/ul>\n<p>4:13 PM:\u00a0<strong>Blood Pressure Reduction Among Acute Ischemic Stroke Patients: A Randomized Controlled Clinical Trial<\/strong><\/p>\n<ul>\n<li>Jiang He, Tulane Univ, New Orleans, LA<\/li>\n<li>Discussant:\u00a0Cathy A Sila, Cleveland, OH<\/li>\n<\/ul>\n<p>4:35 PM:\u00a0<strong>Randomized Clinical Trial of Pre-hospital Induction of Mild Hypothermia in Out-of-Hospital Cardiac Arrest Patients Using a Rapid Infusion of 4oC Normal Saline<\/strong><\/p>\n<ul>\n<li>Francis Kim, Univ of\u00a0Washington, Seattle, WA<\/li>\n<li>Discussant:\u00a0Maaret Castr\u00e9n, Stockholm, Sweden<\/li>\n<\/ul>\n<p>4:57 PM:\u00a0<strong>Target\u00a0Temperature\u00a0Management\u00a033\u00b0C versus 36\u00b0C after Out-of-hospital Cardiac Arrest, a Randomized, Parallel Group, Assessor Blinded Clinical Trial<\/strong><\/p>\n<ul>\n<li>Niklas Nielsen, Helsingborg Hosp, Lund Univ, Helsingborg, Sweden<\/li>\n<li>Discussant:\u00a0Benjamin S Abella, Philadelphia, PA<\/li>\n<\/ul>\n<p>.<\/p>\n<p><strong>Late-Breaking Clinical Trials 2: Prevention: From Schools to Countries<\/strong><\/p>\n<ul>\n<li><em>Monday, Nov 18, 2013, 9:00 AM -10:28 AM<\/em><\/li>\n<\/ul>\n<p>Moderators:<\/p>\n<ul>\n<li>Donna K Arnett, Birmingham, AL<\/li>\n<li>Lynne Braun, Chicago, IL<\/li>\n<\/ul>\n<p>9:00 AM:\u00a0<strong>Promotion of Cardiovascular\u00a0Health\u00a0in Preschool Children: 36-month Cohort Follow-up<\/strong><\/p>\n<ul>\n<li>Jaime C\u00e9spedes, Fundaci\u00f3n CardioInfantil Insto de Cardiolog\u00eda, Bogot\u00e1, Colombia<\/li>\n<li>Discussant:\u00a0Gerard R Martin,\u00a0Washington, DC<\/li>\n<\/ul>\n<p>9:22 AM:\u00a0<strong>Randomized Trial of Social Network\u00a0Lifestyle\u00a0Intervention for Obesity: MICROCLINIC Intervention Results and 16-Month Followup<\/strong><\/p>\n<ul>\n<li>Eric L Ding, Harvard Sch of Public\u00a0Health, Boston, MA<\/li>\n<li>Discussant:\u00a0Lawrence J Appel, Baltimore, MD<\/li>\n<\/ul>\n<p>9:44 AM: \u00a0<strong>Multifaceted Intervention to Improve Medication Adherence and Secondary Prevention Measures (Medication Study) After Acute Coronary Syndrome Hospital Discharge<\/strong><\/p>\n<ul>\n<li>Michael Ho, VA Eastern Colorado\u00a0Health\u00a0Care System, Denver, CO<\/li>\n<li>Discussant:\u00a0Nancy Albert, Cleveland, OH<\/li>\n<\/ul>\n<p>10:06 AM:\u00a0<strong>China Rural\u00a0Health\u00a0Initiative &#8211; Sodium Reduction Study: the Effects of a Community-Based Sodium Reduction Program on 24hr Urinary Sodium and Blood Pressure in Rural China<\/strong><\/p>\n<ul>\n<li>Nicole Li, The George Inst for Global\u00a0Health, Sydney, Australia<\/li>\n<\/ul>\n<div>\n<p>.<\/p>\n<p><strong>Late-Breaking Clinical Trials 3:\u00a0Medical and Surgical Approaches to Improving Heart Failure Outcomes<\/strong><\/p>\n<ul>\n<li><em>Monday, Nov 18, 2013, 10:45 AM -12:13 PM<\/em><\/li>\n<\/ul>\n<p>Moderators:<\/p>\n<ul>\n<li>Frederick A Masoudi, Aurora, CO<\/li>\n<li>Adrian F Hernandez, Durham, NC<\/li>\n<\/ul>\n<p>10:45 AM:\u00a0<strong>Atrial Antitachycardia Pacing and Managed Ventricular Pacing Reduce the Endpoint Composed by Death, Cardiovascular Hospitalizations and Permanent Atrial Fibrillation Compared to Conventional Dual Chamber Pacing in Bradycardia Patients: Results of the Minerva Randomized Study<\/strong><\/p>\n<ul>\n<li>Giuseppe Boriani, Univ of Bologna, Policlinico S.Orsola-Malpighi, Bologna, Bologna, Italy<\/li>\n<li>Discussant:\u00a0Anthony Tang, Victoria, BC, Canada<\/li>\n<\/ul>\n<p>11:07 AM:\u00a0<strong>Renal Optimization\u00a0Strategies\u00a0Evaluation in Acute Heart Failure (ROSE AHF) Trial<\/strong><\/p>\n<ul>\n<li>Horng H Chen, MAYO Clinic, Rochester, MN<\/li>\n<li>Discussant:\u00a0Marco Metra, Brescia, Italy<\/li>\n<\/ul>\n<p>11:29 AM:\u00a0<strong>Severe Ischemic Mitral Regurgitation: Is it Better to Repair or Replace the Valve?<\/strong><\/p>\n<ul>\n<li>Michael A Acker, Hosp of the Univ of Pennsylvania, Philadelphia, PA<\/li>\n<li>Discussant:\u00a0Timothy J Gardner, Newark, DE<\/li>\n<\/ul>\n<p>11:51 AM:\u00a0<strong>Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist (TOPCAT)<\/strong><\/p>\n<ul>\n<li>Marc A. Pfeffer, Brigham &amp; Women&#8217;s Hosp, Harvard, Boston, MA<\/li>\n<li>Discussant:\u00a0Margaret M Redfield, Rochester, MN<\/li>\n<\/ul>\n<p>.<\/p>\n<p><strong>Late-Breaking Clinical Trials 4:\u00a0Therapeutic Advances in Coronary and Peripheral Vascular Disease.<\/strong><\/p>\n<ul>\n<li><em>Monday, Nov 18, 2013, 3:45 PM &#8211; 5:13 PM<\/em><\/li>\n<\/ul>\n<p>Moderators:<\/p>\n<ul>\n<li>John G Harold,\u00a0Washington, DC<\/li>\n<li>Mark A Creager, Boston, MA<\/li>\n<\/ul>\n<p>3:45 PM:\u00a0<strong>One Year Mortality in STEMI Patients Randomized to Primary PCI or a Pharmaco-invasive Strategy. The Stream 1 Year Follow-up<\/strong><\/p>\n<ul>\n<li>Peter Sinnaeve, Univ of Leuven, Leuven, Belgium<\/li>\n<li>Discussant:\u00a0Harold Dauerman, Burlington, VT<\/li>\n<\/ul>\n<p>4:07 PM:\u00a0<strong>Secretory Phospholipase A2 Inhibition with Varespladib and Cardiovascular Events in Patients with an Acute Coronary Syndrome: Results of the VISTA-16 Study<\/strong><\/p>\n<ul>\n<li>Stephen Nicholls, South Australian\u00a0Health\u00a0and Medical Res Inst, Adelaide, Australia<\/li>\n<li>Discussant:\u00a0Philippe Gabriel Steg, Paris, France<\/li>\n<\/ul>\n<p>4:29 PM:\u00a0<strong>Randomized Comparison of Endovascular Revascularization Plus Supervised Exercise Therapy Versus Supervised Exercise Therapy Only in Patients With Peripheral Artery Disease and Intermittent Claudication: Results of the Endovascular Revascularization and Supervised Exercise (ERASE) Trial<\/strong><\/p>\n<ul>\n<li>Farzin Fakhry, Erasmus MC, Rotterdam, Netherlands<\/li>\n<li>Discussant:\u00a0Mary McDermott, Chicago, IL<\/li>\n<\/ul>\n<p>4:51 PM:\u00a0<strong>A Randomized Multicenter Clinical Trial of Renal Artery Stenting in Preventing Cardiovascular and Renal Events: Results of the CORAL Study<\/strong><\/p>\n<ul>\n<li>Christopher J Cooper, Univ of Toledo, Toledo, OH<\/li>\n<li>Discussant:\u00a0Thomas Zeller, Bad Krozingen, Germany<\/li>\n<\/ul>\n<div>.<\/div>\n<p><strong>Late-Breaking Clinical Trials 5:\u00a0New\u00a0Strategies\u00a0for Atrial Fibrillation Patients: Rhythm and Thrombosis<\/strong><\/p>\n<ul>\n<li>Tuesday, Nov 19, 2013, 10:45 AM -12:03 PM<\/li>\n<\/ul>\n<p>Moderators:<\/p>\n<ul>\n<li>Augustus O Grant, Durham, NC<\/li>\n<li>Keith A\u00a0Fox, Edinburgh, United Kingdom<\/li>\n<\/ul>\n<p>10:45 AM:\u00a0<strong>RADAR-AF Trial. A Randomized Multicenter Comparison of Radiofrequency Catheter Ablation of Drivers versus Circumferential Pulmonary Vein Isolation in Patients with Atrial Fibrillation<\/strong><\/p>\n<ul>\n<li>Felipe Atienza, Hosp Gregorio Maranon, Madrid, Spain<\/li>\n<li>Discussant:\u00a0Mark Link, Boston, MA<\/li>\n<\/ul>\n<p>11:07 AM:\u00a0<strong>A Randomized Trial Comparing Genotype-Guided Dosing of Warfarin to Standard Dosing: The EU Pharmacogenetics of Anticoagulant Therapy (EU-PACT) Warfarin Study<\/strong><\/p>\n<ul>\n<li>Munir Pirmohamed, Univ of\u00a0Liverpool,\u00a0Liverpool, United Kingdom<\/li>\n<\/ul>\n<p>11:17 AM:\u00a0<strong>The Clarification of Optimal Anticoagulation through Genetics (COAG) Trial<\/strong><\/p>\n<ul>\n<li>Stephen E. Kimmel, Univ PA Sch of Med, Philadelphia, PA<\/li>\n<\/ul>\n<p>11:27 AM:\u00a0Discussant of EU-PACT Warfarin Study and COAG Trial:\u00a0Patrick T. Ellinor, Boston, MA<\/p>\n<p>11:41 AM:\u00a0<strong>ENGAGE AF-TIMI 48 Primary Results<\/strong><\/p>\n<ul>\n<li>Robert P Giugliano, Brigham and Women&#8217;s Hosp, Boston, MA<\/li>\n<li>Discussant:\u00a0Elaine Hylek, Boston, MA<\/li>\n<\/ul>\n<\/div>\n<p>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>There are still a few days left in August, and the European Society of Cardiology meeting doesn&#8217;t start until this weekend in Amsterdam. Nevertheless, the\u00a0American Heart Association\u00a0has released the list of late-breaking clinical trials for its annual meeting in November. Late-Breaking Clinical Trials 1:\u00a0Acute Cardiovascular and Cerebrovascular Care Sunday, Nov 17, 2013, 4:00 PM &#8211; [&hellip;]<\/p>\n","protected":false},"author":196,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[495,11,20,13,1,14,9,7,16],"tags":[1306,1641],"class_list":["post-38189","post","type-post","status-publish","format-standard","hentry","category-anticoagulation-2","category-cardiac-imaging","category-cardiac-surgery","category-electrophysiology","category-general","category-heart-failure","category-interventional-cardiology","category-prevention","category-vascular","tag-american-heart-association","tag-late-breaking-clinical-trials"],"_links":{"self":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/38189","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/users\/196"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/comments?post=38189"}],"version-history":[{"count":0,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/38189\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/media?parent=38189"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/categories?post=38189"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/tags?post=38189"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}