{"id":46016,"date":"2014-11-17T12:04:41","date_gmt":"2014-11-17T17:04:41","guid":{"rendered":"http:\/\/blogs.nejm.org\/cardioexchange\/?post_type=voices&p=46016"},"modified":"2014-11-17T12:04:41","modified_gmt":"2014-11-17T17:04:41","slug":"selections-from-richard-lehmans-literature-review-november-17th","status":"publish","type":"post","link":"https:\/\/blogs.nejm.org\/cardioexchange\/2014\/11\/17\/selections-from-richard-lehmans-literature-review-november-17th\/","title":{"rendered":"Selection from Richard Lehman\u2019s Literature Review: November 17th"},"content":{"rendered":"

CardioExchange is pleased to reprint this selection from Dr. Richard Lehman\u2019s\u00a0weekly journal review blog<\/a>\u00a0at\u00a0BMJ.com<\/a>. Selected summaries are relevant to our audience, but we encourage members to engage with the\u00a0entire blog<\/a>.<\/em><\/p>\n

The BMJ<\/em> 15 November 2014 Vol 349<\/strong><\/p>\n

Anticoagulant Therapy During Primary PCI for Acute MI:<\/strong> A confession: these reviews are there to point you to the evidence, but do not constitute proof that I know much. For someone who never does percutaneous coronary interventions, there is simply no use in taking up brain space to try and remember which is the latest anticoagulant regimen to come up top in the meta-analysis stakes. Reporting the trials over the last 16+ years has been fun at times (this is a lie), but you can\u2019t really expect me to remember my dabigatran from my enoxaparin. All it has done is give me a healthy scepticism about the possibility of a truly definitive and up to date meta-analysis. But here is the conclusion of the latest one<\/a>: \u201cIn patients undergoing primary PCI, unfractionated heparin plus GpIIb\/IIIa inhibitor and LMWH plus GpIIb\/IIIa inhibitor were most efficacious, with the lowest rate of major adverse cardiovascular events, whereas bivalirudin was safest, with the lowest bleeding.\u201d I\u2019m a firm believer in shared decision making, but if I was about to undergo PCI, I think my eyes would just glaze over and I\u2019d find myself saying \u201cJust do whatever you think best, doctor.\u201d<\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

This week’s topic is anticoagulant therapy during primary PCI for acute MI.<\/p>\n","protected":false},"author":475,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-46016","post","type-post","status-publish","format-standard","hentry","category-general"],"_links":{"self":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/46016","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/users\/475"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/comments?post=46016"}],"version-history":[{"count":0,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/46016\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/media?parent=46016"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/categories?post=46016"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/tags?post=46016"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}