{"id":5362,"date":"2010-12-13T16:07:41","date_gmt":"2010-12-13T21:07:41","guid":{"rendered":"http:\/\/blogs.nejm.org\/cardioexchange\/?p=5362"},"modified":"2011-07-19T17:44:40","modified_gmt":"2011-07-19T21:44:40","slug":"false-positive-ct-angiogram-leads-to-heart-transplant","status":"publish","type":"post","link":"https:\/\/blogs.nejm.org\/cardioexchange\/2010\/12\/13\/false-positive-ct-angiogram-leads-to-heart-transplant\/","title":{"rendered":"False-Positive CT Angiogram Leads to Heart Transplant"},"content":{"rendered":"<p>A 52-year old woman with atypical chest pain ended up with a heart transplant after a CT angiogram to &#8220;reassure&#8221; her sparked a devastating sequence of events. Following a false-positive CT angiogram, the patient underwent coronary angiography and suffered a dissection of the left main coronary artery, followed by emergency CABG, subsequent graft failure, and multiple additional complications. The case report from the Cleveland Clinic is <a href=\"http:\/\/archinte.ama-assn.org\/cgi\/content\/short\/archinternmed.2010.464\">published online in the <em>Archives of Internal Medicine<\/em><\/a>.<\/p>\n<p>&#8220;We believe that in this case the unwarranted use of advanced diagnostic imaging (false-positive CCTA findings) directly contributed to unnecessary cardiac catheterization that resulted in a tragic complication and significant morbidity,&#8221; write the authors. &#8220;In an era in which comparative efficacy of therapies has assumed critical importance, the unchecked growth of CCTA seems not only unfounded but also irresponsible and unsustainable.&#8221;<\/p>\n<p>In an <a href=\"http:\/\/archinte.ama-assn.org\/cgi\/content\/extract\/archinternmed.2010.465v1\">accompanying editorial<\/a>, <em>Archives<\/em> editor Rita Redberg and colleagues write that the case is another illustration that &#8220;less is more &#8230; if a test is not sufficiently accurate to change clinical management in a particular setting, it should not be done.&#8221;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A 52-year old woman with atypical chest pain ended up with a heart transplant after a CT angiogram to &#8220;reassure&#8221; her sparked a devastating sequence of events. Following a false-positive CT angiogram, the patient underwent coronary angiography and suffered a dissection of the left main coronary artery, followed by emergency CABG, subsequent graft failure, and [&hellip;]<\/p>\n","protected":false},"author":196,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[11,20,14],"tags":[231,503,617,618],"class_list":["post-5362","post","type-post","status-publish","format-standard","hentry","category-cardiac-imaging","category-cardiac-surgery","category-heart-failure","tag-cabg","tag-ct-angiography","tag-cta","tag-transplantation"],"_links":{"self":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/5362","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/users\/196"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/comments?post=5362"}],"version-history":[{"count":0,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/5362\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/media?parent=5362"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/categories?post=5362"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/tags?post=5362"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}