{"id":5383,"date":"2010-12-14T14:15:22","date_gmt":"2010-12-14T19:15:22","guid":{"rendered":"http:\/\/blogs.nejm.org\/cardioexchange\/?p=5383"},"modified":"2011-07-19T17:44:40","modified_gmt":"2011-07-19T21:44:40","slug":"study-finds-inverse-correlation-between-hdl-and-alzheimers","status":"publish","type":"post","link":"https:\/\/blogs.nejm.org\/cardioexchange\/2010\/12\/14\/study-finds-inverse-correlation-between-hdl-and-alzheimers\/","title":{"rendered":"Study Finds Inverse Correlation Between HDL and Alzheimer&#8217;s"},"content":{"rendered":"<p>High levels of HDL are linked to a lower risk for Alzheimer&#8217;s disease (AD), according to <a href=\"http:\/\/archneur.ama-assn.org\/cgi\/content\/short\/67\/12\/1491\">a new study published in <\/a><em><a href=\"http:\/\/archneur.ama-assn.org\/cgi\/content\/short\/67\/12\/1491\">Archives of Neurology<\/a>. <\/em>Researchers at Columbia University followed 1,130 Medicare recipients in New York City with no cognitive impairment. After 4,469 person-years of follow-up, they identified 101 cases of AD (89 probable and 12 possible). High HDL was associated with a reduced risk for AD after adjusting for age, sex, education, ethnicity, and <em>APOEe4<\/em> genotype.<\/p>\n<p>The authors caution that their results may not apply to other populations: \u201cAn important consideration in the interpretation of the results is that it was conducted in an urban multiethnic elderly community with a high prevalence of risk factors for mortality and dementia. Thus, our results may not be generalizeable to cohorts with younger individuals or to cohorts with participants with a lower morbidity [disease] burden.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>High levels of HDL are linked to a lower risk for Alzheimer&#8217;s disease (AD), according to a new study published in Archives of Neurology. Researchers at Columbia University followed 1,130 Medicare recipients in New York City with no cognitive impairment. After 4,469 person-years of follow-up, they identified 101 cases of AD (89 probable and 12 [&hellip;]<\/p>\n","protected":false},"author":196,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7,16],"tags":[619,209],"class_list":["post-5383","post","type-post","status-publish","format-standard","hentry","category-prevention","category-vascular","tag-alzheimers-disease-2","tag-hdl"],"_links":{"self":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/5383","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/users\/196"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/comments?post=5383"}],"version-history":[{"count":0,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/5383\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/media?parent=5383"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/categories?post=5383"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/tags?post=5383"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}