{"id":5457,"date":"2010-12-20T16:04:21","date_gmt":"2010-12-20T21:04:21","guid":{"rendered":"http:\/\/blogs.nejm.org\/cardioexchange\/?p=5457"},"modified":"2011-07-19T17:44:40","modified_gmt":"2011-07-19T21:44:40","slug":"dronedarone-rate-control-and-catheter-ablation-incorporated-in-updated-af-guidelines","status":"publish","type":"post","link":"https:\/\/blogs.nejm.org\/cardioexchange\/2010\/12\/20\/dronedarone-rate-control-and-catheter-ablation-incorporated-in-updated-af-guidelines\/","title":{"rendered":"Dronedarone, Rate Control, and Catheter Ablation Incorporated in Updated AF Guidelines"},"content":{"rendered":"<p>A <a href=\"http:\/\/circ.ahajournals.org\/cgi\/reprint\/CIR.0b013e3181fa3cf4v1\">focused update on the guidelines for the management of atrial fibrillation<\/a> has been released by the American College of Cardiology, American Heart Association, and Heart Rhythm Society. Most notably, the new guidelines incorporate recent data from clinical trials evaluating dronedarone, clopidogrel, strict rate control, and catheter ablation. Here are the major highlights:<\/p>\n<ul>\n<li>Dronedarone can reduce CV hospitalizations related to AF but should not be given to patients with class IV heart failure or those who have had a recent episode of decompensated heart failure.<\/li>\n<li>Clopidogrel in addition to aspirin &#8220;might be considered&#8221; for stroke prevention in patients who cannot take warfarin.<\/li>\n<li>Strict heart rate control is no better than lenient rate control.<\/li>\n<li>Catheter ablation gains a class 1 recommendation when performed in experienced centers for selected patients who have failed antiarrhythmic drug therapy and have normal or mildly dilated left atria, normal or mildly reduced LV function, and no severe pulmonary disease. Catheter ablation is also a reasonable option to treat symptomatic persistent AF and symptomatic paroxysmal AF in patients with significant \u00a0left atrial dilation or with significant LV dysfunction.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>A focused update on the guidelines for the management of atrial fibrillation has been released by the American College of Cardiology, American Heart Association, and Heart Rhythm Society. Most notably, the new guidelines incorporate recent data from clinical trials evaluating dronedarone, clopidogrel, strict rate control, and catheter ablation. Here are the major highlights: Dronedarone can [&hellip;]<\/p>\n","protected":false},"author":196,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[365,341,342,489],"class_list":["post-5457","post","type-post","status-publish","format-standard","hentry","category-electrophysiology","tag-af","tag-atrial-fibrillation","tag-spaf","tag-stroke-prevention"],"_links":{"self":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/5457","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/users\/196"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/comments?post=5457"}],"version-history":[{"count":0,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/5457\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/media?parent=5457"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/categories?post=5457"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/tags?post=5457"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}