{"id":5485,"date":"2010-12-22T10:06:08","date_gmt":"2010-12-22T15:06:08","guid":{"rendered":"http:\/\/blogs.nejm.org\/cardioexchange\/?p=5485"},"modified":"2011-07-19T17:45:21","modified_gmt":"2011-07-19T21:45:21","slug":"deepak-bhatt-looking-back-at-2010-and-ahead-to-2011","status":"publish","type":"post","link":"https:\/\/blogs.nejm.org\/cardioexchange\/2010\/12\/22\/deepak-bhatt-looking-back-at-2010-and-ahead-to-2011\/","title":{"rendered":"Deepak Bhatt: Looking Back at 2010 and Ahead to 2011"},"content":{"rendered":"<p><em>To celebrate the holiday season,\u00a0<strong>CardioExchange<\/strong> asked several of our contributors to choose the 3 most important cardiology-related events of the past year and to make 3 predictions for 2011.<\/em><\/p>\n<p><strong><em>Looking back at 2010:<\/em><\/strong><\/p>\n<p style=\"padding-left: 30px;\">1. <a href=\"http:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa1008232\">PARTNER<\/a>: Transcatheter aortic valve implantation significantly improved symptoms and reduced mortality in patients with severe aortic stenosis who were not candidates for surgery. <em>The treatment of valvular heart disease is forever changed.<\/em><\/p>\n<p style=\"padding-left: 30px;\">2. <a href=\"http:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa1009540\">RAFT<\/a>: CRT when added to an ICD reduced heart failure hospitalizations and reduced mortality in an easily identified group of patients with heart failure.<br \/>\n<em>We can indeed identify patients in whom device therapy is highly effective.<\/em><\/p>\n<p style=\"padding-left: 30px;\">3. <a href=\"http:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa1009744\">DEFINE<\/a>:\u00a0The increases in HDL and reductions in LDL were quite impressive, with no apparent off-target toxicities. <em>If the clinical outcome trial looks as good, anacetrapib will be a major breakthrough in cardiovascular medicine.<\/em><\/p>\n<p><strong><em>Predictions for 2011:<\/em><\/strong><\/p>\n<p style=\"padding-left: 30px;\">1. Increased focus on health care costs, which will nevertheless continue to increase. De facto rationing will start to emerge (though it will not be called that).<\/p>\n<p style=\"padding-left: 30px;\">2. Increased scrutiny of appropriateness of cardiology procedures and cardiac imaging. Will paradoxically lead to many cases of inappropriate underutilization of these technologies.<\/p>\n<p style=\"padding-left: 30px;\">3. Further consolidation among cardiology practices and hospitals. Solo cardiology practice will continue to disappear and more cardiologists will become employees of hospitals; costs will rise, not fall.<\/p>\n<div id=\"_mcePaste\" style=\"position: absolute; left: -10000px; top: 0px; width: 1px; height: 1px; overflow: hidden;\">1. PARTNER: Transcatheter aortic valve implantation significantly improved<br \/>\nsymptoms and reduced mortality in patients with severe aortic stenosis who were<br \/>\nnot candidates for surgery. The treatment of valvular heart disease is forever<br \/>\nchanged.<br \/>\n2. RAFT &#8211; CRT when added to an ICD reduced heart failure hospitalizations and<br \/>\nreduced mortality in an easily identified group of patients with heart failure.<br \/>\nWe can indeed identify patients in whom device therapy is highly effective.<br \/>\n3. DEFINE: The increases in HDL and reductions in LDL were quite impressive,<br \/>\nwith no apparent off-target toxicities. If the clinical outcome trial looks as<br \/>\ngood, anacetrapib will be a major breakthrough in cardiovascular medicine.<\/div>\n","protected":false},"excerpt":{"rendered":"<p>To celebrate the holiday season,\u00a0CardioExchange asked several of our contributors to choose the 3 most important cardiology-related events of the past year and to make 3 predictions for 2011. Looking back at 2010: 1. PARTNER: Transcatheter aortic valve implantation significantly improved symptoms and reduced mortality in patients with severe aortic stenosis who were not candidates [&hellip;]<\/p>\n","protected":false},"author":196,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[625],"class_list":["post-5485","post","type-post","status-publish","format-standard","hentry","category-general","tag-reviews-and-predictions"],"_links":{"self":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/5485","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/users\/196"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/comments?post=5485"}],"version-history":[{"count":0,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/5485\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/media?parent=5485"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/categories?post=5485"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/tags?post=5485"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}