{"id":5901,"date":"2011-01-12T17:54:23","date_gmt":"2011-01-12T22:54:23","guid":{"rendered":"http:\/\/blogs.nejm.org\/cardioexchange\/?p=5901"},"modified":"2011-07-19T17:44:14","modified_gmt":"2011-07-19T21:44:14","slug":"maybe-tavi-is-not-all-it%e2%80%99s-cracked-up-to-be","status":"publish","type":"post","link":"https:\/\/blogs.nejm.org\/cardioexchange\/2011\/01\/12\/maybe-tavi-is-not-all-it%e2%80%99s-cracked-up-to-be\/","title":{"rendered":"Maybe TAVI Is Not All It\u2019s Cracked Up To Be"},"content":{"rendered":"<p>The <a href=\"http:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMoa1008232\">PARTNER <\/a>trial of transcatheter aortic valve implantation (TAVI) for severe aortic stenosis was among the hottest cardiology stories of 2010.\u00a0 Now that the hype is receding, some are questioning whether TAVI is ready for prime time.<\/p>\n<p>In <a href=\"http:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMc1013283\">three letters to the Editor of the New England Journal of Medicine<\/a>, our colleagues point out that the \u201cconventional treatment\u201d group received a rather unconventional treatment (aortic balloon valvuloplasty) and had a higher average EuroSCORE (i.e., estimated mortality) than those treated with TAVI, which may have exaggerated the benefit of TAVI.<\/p>\n<p>In considering the demonstrated increase in periprocedural strokes and bleeding complications with TAVI and the patient population most likely to undergo the procedure (i.e., the elderly with multiple coexisting conditions, limited life expectancy, and disproportionate health care expenditures), some are calling for an analysis of the cost-effectiveness and quality-of-life benefits of TAVI.<\/p>\n<p>On the basis of the available information, are you ready to recommend TAVI to your patients?<\/p>\n<p>If not, what additional information would you convince you to do so?<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The PARTNER trial of transcatheter aortic valve implantation (TAVI) for severe aortic stenosis was among the hottest cardiology stories of 2010.\u00a0 Now that the hype is receding, some are questioning whether TAVI is ready for prime time. In three letters to the Editor of the New England Journal of Medicine, our colleagues point out that [&hellip;]<\/p>\n","protected":false},"author":214,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1,9],"tags":[429,396,423],"class_list":["post-5901","post","type-post","status-publish","format-standard","hentry","category-general","category-interventional-cardiology","tag-aortic-valve-stenosis","tag-partner","tag-tavi"],"_links":{"self":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/5901","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/users\/214"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/comments?post=5901"}],"version-history":[{"count":0,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/5901\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/media?parent=5901"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/categories?post=5901"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/tags?post=5901"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}