{"id":6640,"date":"2011-02-25T17:23:17","date_gmt":"2011-02-25T22:23:17","guid":{"rendered":"http:\/\/blogs.nejm.org\/cardioexchange\/?p=6640"},"modified":"2011-07-19T17:44:32","modified_gmt":"2011-07-19T21:44:32","slug":"fda-approves-azilsartan-medoxomil-edarbi-for-high-blood-pressure","status":"publish","type":"post","link":"https:\/\/blogs.nejm.org\/cardioexchange\/2011\/02\/25\/fda-approves-azilsartan-medoxomil-edarbi-for-high-blood-pressure\/","title":{"rendered":"FDA Approves Azilsartan Medoxomil (Edarbi) for High Blood Pressure"},"content":{"rendered":"<p><a href=\"http:\/\/www.fda.gov\/NewsEvents\/Newsroom\/PressAnnouncements\/ucm244722.htm\">The FDA has approved azilsartan medoxomil (Edarbi, Takeda) for the treatment of high blood pressure.<\/a> The new\u00a0angiotensin II receptor blocker (ARB)\u00a0will be available in 80 mg and 40 mg doses. The recommended dose is 80 mg once daily. The 40 mg dose is used in combination with a diuretic.<\/p>\n<p>The FDA said that, in clinical studies, azilsartan medoxomil was more effective than valsartan (Diovan) and olmesartan (Benicar) in lowering 24-hour blood pressure.<\/p>\n<p>In a separate development, <a href=\"http:\/\/www.takeda.com\/press\/article_40219.html\">Takeda announced yesterday<\/a> that it had submitted an NDA for a\u00a0fixed-dose combination of azilsartan medoxomil plus chlorthalidone.<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The FDA has approved azilsartan medoxomil (Edarbi, Takeda) for the treatment of high blood pressure. The new\u00a0angiotensin II receptor blocker (ARB)\u00a0will be available in 80 mg and 40 mg doses. The recommended dose is 80 mg once daily. The 40 mg dose is used in combination with a diuretic. The FDA said that, in clinical [&hellip;]<\/p>\n","protected":false},"author":196,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1,7],"tags":[675,647,713,714],"class_list":["post-6640","post","type-post","status-publish","format-standard","hentry","category-general","category-prevention","tag-antihypertensives","tag-arbs","tag-azilsartan","tag-high-blood-pressure"],"_links":{"self":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/6640","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/users\/196"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/comments?post=6640"}],"version-history":[{"count":0,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/6640\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/media?parent=6640"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/categories?post=6640"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/tags?post=6640"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}