{"id":7228,"date":"2011-03-29T12:10:30","date_gmt":"2011-03-29T16:10:30","guid":{"rendered":"http:\/\/blogs.nejm.org\/cardioexchange\/?p=7228"},"modified":"2011-07-19T17:44:29","modified_gmt":"2011-07-19T21:44:29","slug":"conflicts-of-interest-in-cardiovascular-guidelines","status":"publish","type":"post","link":"https:\/\/blogs.nejm.org\/cardioexchange\/2011\/03\/29\/conflicts-of-interest-in-cardiovascular-guidelines\/","title":{"rendered":"Conflicts of Interest in Cardiovascular Guidelines"},"content":{"rendered":"<p>More than half of authors and reviewers of cardiovascular clinical  practice guidelines (CPGs) have at least one conflict of interest (COI),  according to <a href=\"http:\/\/archinte.ama-assn.org\/cgi\/content\/full\/171\/6\/577\">a  study in the <em>Archives of Internal Medicine.<\/em><\/a><em> <\/em> Todd  Mendelson and colleagues analyzed the 17 most recent ACC\/AHA CPGs  through 2008 and found that 56% of the participants reported a COI. The  most common COI was being a consultant or a member of an advisory board.<\/p>\n<p>The authors conclude that &#8220;although restricting participation may  prevent some qualified individuals  from serving in the guidelines  production process, we found that a  large percentage of individuals  with guidelines experience reported  no disclosures, suggesting there is  a substantial pool of potential guideline  writers and reviewers without COIs.&#8221;<\/p>\n<p>In <a href=\"http:\/\/archinte.ama-assn.org\/cgi\/content\/full\/171\/6\/584\">an  accompanying commentary<\/a>, Steve Nissen writes that the authors &#8220;raise  disturbing questions about the independence and reliability of CPGs in  cardiovascular medicine&#8221; and that &#8220;the depth and breath of industry  relationships&#8230; are extraordinary.&#8221; Nissen also notes that  &#8220;professional societies and their leadership are often plagued by the  same commercial relationships as the CPG-writing committees.&#8221;<\/p>\n<p>In response to the <em>Archives<\/em> article and <a href=\"http:\/\/www.iom.edu\/Reports\/2011\/Clinical-Practice-Guidelines-We-Can-Trust.aspx\">an  IOM report on CPGs<\/a>, <a href=\"http:\/\/www.newsroom.heart.org\/index.php?s=43&amp;item=1300\">the  AHA and the ACC issued a statement <\/a>pointing out that the two groups had &#8220;refined their policies in 2010 to require  even more  stringent management of relationships with industry, to align  with the  Council of Medical Specialty Societies (CMSS). Thus the data  within and  the conclusions drawn by the article do not reflect the  reality of the  guidelines development process today.&#8221;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>More than half of authors and reviewers of cardiovascular clinical practice guidelines (CPGs) have at least one conflict of interest (COI), according to a study in the Archives of Internal Medicine. Todd Mendelson and colleagues analyzed the 17 most recent ACC\/AHA CPGs through 2008 and found that 56% of the participants reported a COI. The [&hellip;]<\/p>\n","protected":false},"author":196,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[201,595],"class_list":["post-7228","post","type-post","status-publish","format-standard","hentry","category-general","tag-conflict-of-interest","tag-guidelines"],"_links":{"self":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/7228","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/users\/196"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/comments?post=7228"}],"version-history":[{"count":0,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/7228\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/media?parent=7228"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/categories?post=7228"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/tags?post=7228"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}