{"id":7784,"date":"2011-04-12T16:04:36","date_gmt":"2011-04-12T20:04:36","guid":{"rendered":"http:\/\/blogs.nejm.org\/cardioexchange\/?p=7784"},"modified":"2011-07-19T17:44:28","modified_gmt":"2011-07-19T21:44:28","slug":"particle-trap-reduces-harmful-diesel-emissions-could-be-cardioprotective","status":"publish","type":"post","link":"https:\/\/blogs.nejm.org\/cardioexchange\/2011\/04\/12\/particle-trap-reduces-harmful-diesel-emissions-could-be-cardioprotective\/","title":{"rendered":"Particle Trap Reduces Harmful Diesel Emissions, Could Be Cardioprotective"},"content":{"rendered":"<p>A commonly available particle trap can dramatically reduce harmful  emissions from diesel engines and may prevent adverse cardiovascular  effects from the emissions, according to <a href=\"http:\/\/circ.ahajournals.org\/cgi\/content\/abstract\/CIRCULATIONAHA.110.987263v1\">a  new study published in <em>Circulation<\/em><\/a>. In a randomized,  double-blind, three-way crossover trial, Andrew Lucking and colleagues  compared the effects of filtered air to diesel exhaust with or without a  particle trap for 1 hour in 19 healthy male volunteers.<\/p>\n<p>They report that the particle trap reduced\u00a0 both the number of particle  emissions (by more  than a factor of 1000) and their size (from 320 to 7.2 \u00b5g\/m3). This was associated with increased vasodilatation, reduced  thrombus formation, and increased tPA release. No adverse effects  appeared to be associated with the particle trap. The authors conclude:  &#8220;Given these beneficial effects on biomarkers of cardiovascular health,  the widespread use of particle traps on diesel-powered vehicles may have  substantial public health benefit and reduce the burden of  cardiovascular disease.&#8221;<\/p>\n<p>In <a href=\"http:\/\/circ.ahajournals.org\/cgi\/reprint\/CIRCULATIONAHA.111.021881v1\">an accompanying editorial<\/a>, Robert Brook and Jeffrey Brook (chair and author, respectively, of<a href=\"http:\/\/circ.ahajournals.org\/cgi\/reprint\/CIR.0b013e3181dbece1\"> the AHA&#8217;s scientific statement on air pollution and cardiovascular   disease<\/a>) write that &#8220;given the paucity of human data, these new  findings carry substantial weight&#8221; and &#8220;support ongoing efforts to  reduce particle pollution through programs targeting diesel emissions.&#8221;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A commonly available particle trap can dramatically reduce harmful emissions from diesel engines and may prevent adverse cardiovascular effects from the emissions, according to a new study published in Circulation. In a randomized, double-blind, three-way crossover trial, Andrew Lucking and colleagues compared the effects of filtered air to diesel exhaust with or without a particle [&hellip;]<\/p>\n","protected":false},"author":196,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[709],"class_list":["post-7784","post","type-post","status-publish","format-standard","hentry","category-prevention","tag-air-pollution"],"_links":{"self":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/7784","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/users\/196"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/comments?post=7784"}],"version-history":[{"count":0,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/7784\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/media?parent=7784"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/categories?post=7784"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/tags?post=7784"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}