{"id":9037,"date":"2011-06-28T15:56:26","date_gmt":"2011-06-28T19:56:26","guid":{"rendered":"http:\/\/blogs.nejm.org\/cardioexchange\/?p=9037"},"modified":"2011-07-19T17:44:21","modified_gmt":"2011-07-19T21:44:21","slug":"diastolic-dysfunction-linked-to-mortality","status":"publish","type":"post","link":"https:\/\/blogs.nejm.org\/cardioexchange\/2011\/06\/28\/diastolic-dysfunction-linked-to-mortality\/","title":{"rendered":"Diastolic Dysfunction Linked to Mortality"},"content":{"rendered":"<p>A new study sheds light on the prognostic value of diastolic dysfunction (DD) in patients with normal systolic function. In <a href=\"http:\/\/archinte.ama-assn.org\/cgi\/content\/full\/171\/12\/1082\">a study published in the <em>Archives of Internal Medicine<\/em><\/a>, Carmel Halley and colleagues reviewed echocardiograms from 36,261 consecutive patients who were found to have normal systolic function. Nearly two thirds (65.2%) had some degree of DD.<\/p>\n<p>There were 5789 deaths during 6.2 years of follow-up. The greater the degree of diastolic dysfunction, the higher the mortality rate:<\/p>\n<ul>\n<li>normal diastolic function: 7% mortality<\/li>\n<li>mild DD: 21% mortality<\/li>\n<li>moderate DD: 24% mortality<\/li>\n<li>severe DD: 39% mortality<\/li>\n<\/ul>\n<p>In a separate analysis using propensity matching, only moderate and severe DD were significantly associated with mortality.<\/p>\n<p>In <a href=\"http:\/\/archinte.ama-assn.org\/cgi\/content\/full\/171\/12\/1088\">an invited commentary<\/a>, Ileana Pi\u00f1a writes that the study provides important new information about DD, informing physicians that DD is common and that physicians should &#8220;be aware of the prognostic value of moderate and severe DD.&#8221; But the study does not appear to shed light on the large group of elderly women who present with acute heart failure, she writes.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A new study sheds light on the prognostic value of diastolic dysfunction (DD) in patients with normal systolic function. In a study published in the Archives of Internal Medicine, Carmel Halley and colleagues reviewed echocardiograms from 36,261 consecutive patients who were found to have normal systolic function. Nearly two thirds (65.2%) had some degree of [&hellip;]<\/p>\n","protected":false},"author":196,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[14],"tags":[892],"class_list":["post-9037","post","type-post","status-publish","format-standard","hentry","category-heart-failure","tag-diastolic-dysfunction"],"_links":{"self":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/9037","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/users\/196"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/comments?post=9037"}],"version-history":[{"count":0,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/posts\/9037\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/media?parent=9037"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/categories?post=9037"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.nejm.org\/cardioexchange\/wp-json\/wp\/v2\/tags?post=9037"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}