For at least a decade, people\u00a0suggested that GERD was more than just heartburn and regurgitation, that it might also account for all the wheezing, coughing, and throat clearing we were\u00a0encountering in the clinic. This\u00a0idea led to the\u00a0notion that we should try high-dose acid-suppression therapy in\u00a0these other \u201cGERD\u201d patients.<\/p>\n
What has recently become clear, however,\u00a0is that\u00a0most of these\u00a0patients don’t actually\u00a0have GERD at all — and even\u00a0when they do, empirical high-dose PPI therapy does not improve their non-reflux symptoms.\u00a0 The latest example of this comes from an RCT just published in the New England Journal of\u00a0Medicine<\/a>.<\/p>\n Despite\u00a0this evidence,\u00a0the belief that GERD accounts for a large proportion of airway symptoms seems tough to crack. What do you do when you encounter a patient whose cough, hoarseness, or wheezing has been blamed on GERD?<\/p>\n","protected":false},"excerpt":{"rendered":" For at least a decade, people\u00a0suggested that GERD was more than just heartburn and regurgitation, that it might also account for all the wheezing, coughing, and throat clearing we were\u00a0encountering in the clinic. This\u00a0idea led to the\u00a0notion that we should try high-dose acid-suppression therapy in\u00a0these other \u201cGERD\u201d patients. What has recently become clear, however,\u00a0is that\u00a0most […]<\/p>\n","protected":false},"author":28,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-120","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"_links":{"self":[{"href":"https:\/\/blogs.nejm.org\/gastroenterology\/index.php\/wp-json\/wp\/v2\/posts\/120","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.nejm.org\/gastroenterology\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.nejm.org\/gastroenterology\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/gastroenterology\/index.php\/wp-json\/wp\/v2\/users\/28"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/gastroenterology\/index.php\/wp-json\/wp\/v2\/comments?post=120"}],"version-history":[{"count":0,"href":"https:\/\/blogs.nejm.org\/gastroenterology\/index.php\/wp-json\/wp\/v2\/posts\/120\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.nejm.org\/gastroenterology\/index.php\/wp-json\/wp\/v2\/media?parent=120"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.nejm.org\/gastroenterology\/index.php\/wp-json\/wp\/v2\/categories?post=120"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.nejm.org\/gastroenterology\/index.php\/wp-json\/wp\/v2\/tags?post=120"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}