{"id":725,"date":"2012-03-02T11:41:54","date_gmt":"2012-03-02T16:41:54","guid":{"rendered":"http:\/\/blogstemp2.wpengine.com\/?p=725"},"modified":"2012-03-02T11:41:54","modified_gmt":"2012-03-02T16:41:54","slug":"curses-and-blessings-of-aging","status":"publish","type":"post","link":"https:\/\/blogs.nejm.org\/general-medicine\/index.php\/2012\/03\/curses-and-blessings-of-aging\/","title":{"rendered":"Curses and Blessings of Aging"},"content":{"rendered":"

\u00a0It seems that every time I am in clinic, patients bring in supplements they bought to prevent aging. I usually look at the product ingredients, which include vitamins and herbs, and ask myself three questions:<\/p>\n

\"\"<\/a><\/p>\n

1. Why didn\u2019t I market this? I could put vitamins and herbs together and sell it to the baby boomers saying it prevents wrinkles and Alzheimer’s and make myself a nice chunk of change.<\/p>\n

2. Don\u2019t they read the ingredients or ask somebody before spending this money?<\/p>\n

3. See #1.<\/p>\n

When this happens, \u00a0I calmly look at the bottle and usually tell patients that the product doesn\u2019t contain any harmful ingredients\u00a0and advise them that it would be cheaper to take the multivitamin I had already prescribed than spend extra money for this concoction. Everyone is looking for the secret cure to aging that simply doesn\u2019t exist\u2026yet.<\/p>\n

A recent summary <\/a>in Journal Watch<\/em> General Medicine<\/em>\u00a0\u00a0describes a Mayo clinic study in which senescent cells were marked and destroyed with a compound. When transgenic mice carrying the marker were bred with mice that age prematurely, the animals did not develop age-related disorders and other diseases progressed slowly. Although this\u00a0technique\u00a0isn\u2019t being studied in humans yet– and \u00a0probably won\u2019t help my 87-year-old patient do her \u201cBINGO dance,\u201d — the study paves the way for such research to begin and shows promise for younger folks like me.<\/p>\n

\"\"<\/a><\/p>\n

On the flip side, another study <\/a>summarized in Journal Watch<\/em>\u00a0 alluded to overscreening for cancer in elderly patients. This issue actually came up for me and my medical students this morning. When we looked up guidelines about cancer screening, there\u00a0were so many different guidelines, it was hard to know which ones to follow.<\/p>\n

The patient was a 76-year-old man who had his last colonoscopy at age 65, and a recommendation for 10-year follow up was noted. When comparing guidelines, USPSTF recommends screening for adults aged 50-75, National Cancer Institute recommends screening for adults ages 50-80, and the American Cancer Society recommends screening beginning at age 50 with no upper age limit. With my limited experience and the fear that I could miss something, I erred on the side of caution and told the patient that I would like to screen him again, and he declined. I am probably one of the physicians contributing to overscreening of cancer in elderly patients, but guidelines would be a lot easier to follow if there weren\u2019t so many conflicting ones in the first place.\"\"<\/a><\/p>\n

I also find patients less and less apt to actually have tests done as they get older. A patient today excitedly told us she had earned the right to not have mammograms or pap smears by living to the age of 85. When I asked her about the downside of aging she said, \u201cHoney, I\u2019ll deal with my wrinkles just don\u2019t ever ask me to put my legs in stirrups again.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"

\u00a0It seems that every time I am in clinic, patients bring in supplements they bought to prevent aging. I usually look at the product ingredients, which include vitamins and herbs, and ask myself three questions: 1. Why didn\u2019t I market this? I could put vitamins and herbs together and sell it to the baby boomers […]<\/p>\n","protected":false},"author":21,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2,3,4],"tags":[7,26],"class_list":["post-725","post","type-post","status-publish","format-standard","hentry","category-about-residency","category-cases-and-rounds","category-clinical-implications-of-research","tag-aging","tag-evidence-based-medicine"],"yoast_head":"\nCurses and Blessings of Aging - Insights on Residency Training<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/blogs.nejm.org\/general-medicine\/index.php\/2012\/03\/curses-and-blessings-of-aging\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Curses and Blessings of Aging\" \/>\n<meta property=\"og:description\" content=\"\u00a0It seems that every time I am in clinic, patients bring in supplements they bought to prevent aging. 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