{"id":125,"date":"2008-10-27T05:58:51","date_gmt":"2008-10-27T10:58:51","guid":{"rendered":"http:\/\/blogs.nejm.org\/?p=125"},"modified":"2015-06-04T15:31:43","modified_gmt":"2015-06-04T19:31:43","slug":"antibiotics-as-placebos","status":"publish","type":"post","link":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/antibiotics-as-placebos\/2008\/10\/27\/","title":{"rendered":"Antibiotics as Placebos?"},"content":{"rendered":"<div id=\"attachment_127\" style=\"width: 160px\" class=\"wp-caption alignright\"><a href=\"http:\/\/blogs.nejm.org\/hiv-id-observations\/wp-content\/uploads\/sites\/2\/2008\/10\/zithromax1.jpg\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-127\" class=\"size-thumbnail wp-image-127 \" title=\"not an ad\" src=\"http:\/\/blogs.nejm.org\/hiv-id-observations\/wp-content\/uploads\/sites\/2\/2008\/10\/zithromax1.jpg\" alt=\"\" width=\"150\" height=\"150\" \/><\/a><p id=\"caption-attachment-127\" class=\"wp-caption-text\">(Not an ad.)<\/p><\/div>\n<p><a href=\"http:\/\/www.bmj.com\/cgi\/content\/short\/337\/oct23_2\/a1938\" target=\"_blank\">This article <\/a>in the BMJ is geting lots of news:\u00a0 Out of 679 practicing physicians in the United States, about half admitted to prescribing placebos on a regular basis.\u00a0 A &#8220;small but notable proportion (13%) of physicians reported using antibiotics.&#8221;<\/p>\n<p>My first instinct was surprise that the rate was this low,\u00a0but then I remembered that public perception of this practice <a href=\"http:\/\/www.nytimes.com\/2008\/10\/24\/health\/24placebo.html?_r=1&amp;oref=slogin\" target=\"_blank\">might not be so favorable<\/a>.\u00a0 As a result, the appropriate MD response to this news is to be <a href=\"http:\/\/blogs.nejm.org\/hiv-id-observations\/wp-content\/uploads\/sites\/2\/2008\/10\/cr109.jpg\" target=\"_blank\">&#8220;shocked,\u00a0schocked &#8230;&#8221;<\/a> that placebos are being prescribed, and to express grave concern at the ethics of the practice.\u00a0 So undoubtedly some of the doctors surveyed in that study probably didn&#8217;t tell the truth.<\/p>\n<p>From an ID perspective, reading that antibiotics are sometimes used as a placebo is hardly news at all. \u00a0Since about half of the US population <a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/10836770?ordinalpos=5&amp;itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum\" target=\"_self\">believes that antibiotics are helpful for the common cold<\/a>, all a clinician has to do is prescribe a Z-pack for a runny nose to a patient expecting antibiotics, have that patient get better (colds do, after all get better <em>eventually<\/em>), and the practice is reinforced. \u00a0This exact exchange must transpire hundreds of thousands of times a day in doctors&#8217; offices and emergency rooms.<\/p>\n<p>I&#8217;ve written here about <a href=\"http:\/\/blogs.nejm.org\/index.php\/2008\/09\/18\/c-diff-the-cure-for-antibiotic-abuse\/\" target=\"_blank\">one potential cure <\/a>for this problem (C. diff), but it&#8217;s not exactly something you&#8217;d want instituted as a preventive measure. \u00a0<\/p>\n<p>Is there a way to exploit the placebo&#8217;s powerful effect in clinical practice that doesn&#8217;t seem so sneaky? \u00a0And doesn&#8217;t expose patients to medication side effects? \u00a0Here&#8217;s one: \u00a0Our office has a terrific coffee\/tea maker, and I&#8217;ve found that handing a patient with a bad cold a cup of freshly made green tea in a nice mug works wonders. \u00a0I don&#8217;t believe we ever covered that in medical school.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>This article in the BMJ is geting lots of news:\u00a0 Out of 679 practicing physicians in the United States, about half admitted to prescribing placebos on a regular basis.\u00a0 A &#8220;small but notable proportion (13%) of physicians reported using antibiotics.&#8221; My first instinct was surprise that the rate was this low,\u00a0but then I remembered that [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3,5,7,8],"tags":[72,191,197,727,801],"class_list":["post-125","post","type-post","status-publish","format-standard","hentry","category-health-care","category-infectious-diseases","category-misc","category-patient-care","tag-antibiotics","tag-clinical-care","tag-clinical-trials","tag-placebo","tag-resistance"],"post_mailing_queue_ids":[],"_links":{"self":[{"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/posts\/125","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/comments?post=125"}],"version-history":[{"count":0,"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/posts\/125\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/media?parent=125"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/categories?post=125"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/tags?post=125"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}