{"id":1394,"date":"2011-03-01T14:43:01","date_gmt":"2011-03-01T19:43:01","guid":{"rendered":"http:\/\/blogs.nejm.org\/?p=1394"},"modified":"2015-06-04T15:23:55","modified_gmt":"2015-06-04T19:23:55","slug":"like-it-or-not-prep-enters-the-clinic","status":"publish","type":"post","link":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/like-it-or-not-prep-enters-the-clinic\/2011\/03\/01\/","title":{"rendered":"Like It or Not, PrEP Enters the Clinic"},"content":{"rendered":"<p><a href=\"http:\/\/blogs.nejm.org\/hiv-id-observations\/wp-content\/uploads\/sites\/2\/2011\/03\/prexie-stamp-7-cents.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignright size-full wp-image-1396\" title=\"prexie stamp 7 cents\" src=\"http:\/\/blogs.nejm.org\/hiv-id-observations\/wp-content\/uploads\/sites\/2\/2011\/03\/prexie-stamp-7-cents.jpg\" alt=\"\" width=\"191\" height=\"223\" \/><\/a>Since the <a href=\"http:\/\/www.nejm.org\/doi\/pdf\/10.1056\/NEJMoa1011205\" target=\"_blank\">publication of iPrEx<\/a>, the hypothetical decision about whether to prescribe pre-exposure prophylaxis (PrEP) has become a practical reality.<\/p>\n<p>As a result,\u00a0we&#8217;ve posted a <a href=\"http:\/\/aids-clinical-care.jwatch.org\/cgi\/content\/full\/2011\/228\/1\">case<\/a> on the\u00a0<em>Journal Watch\/AIDS Clinical Care <\/em>site,<em> <\/em>describing someone who requests intermittent pre-exposure prophylaxis to prevent HIV.<\/p>\n<p>It&#8217;s a high-risk, HIV-negative man who&#8217;s been treated several times with <em>post-exposure<\/em> prophylaxis. The case was adapted from someone seen recently in our practice, and it raised many questions about what to do in this newly minted area. As there are obviously no &#8220;right&#8221; answers, we had a broad range of responses within our group. We&#8217;ve asked experts in the field to weigh in as well and will publish those responses shortly.<\/p>\n<p>In the meantime, what have you been doing with requests for PrEP? \u00a0Have you found the &#8220;<a href=\"http:\/\/blogs.nejm.org\/index.php\/wow-that-was-fast-prep-guidelines-appear\/2011\/01\/28\/\" target=\"_blank\">Guidance<\/a>&#8221; (note that these are not yet &#8220;Guidelines&#8221;) useful? \u00a0Any helpful or just interesting anecdotes or opinions you wish to share?<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Since the publication of iPrEx, the hypothetical decision about whether to prescribe pre-exposure prophylaxis (PrEP) has become a practical reality. As a result,\u00a0we&#8217;ve posted a case on the\u00a0Journal Watch\/AIDS Clinical Care site, describing someone who requests intermittent pre-exposure prophylaxis to prevent HIV. It&#8217;s a high-risk, HIV-negative man who&#8217;s been treated several times with post-exposure prophylaxis. [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2,4,8,9],"tags":[423,745,748,902,908,950],"class_list":["post-1394","post","type-post","status-publish","format-standard","hentry","category-antiretroviral-rounds","category-hiv","category-patient-care","category-policy","tag-hiv","tag-pre-exposure-prophylaxis","tag-prep","tag-tdfftc","tag-tenofovir","tag-truvada"],"post_mailing_queue_ids":[],"_links":{"self":[{"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/posts\/1394","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/comments?post=1394"}],"version-history":[{"count":0,"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/posts\/1394\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/media?parent=1394"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/categories?post=1394"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/tags?post=1394"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}