{"id":2028,"date":"2011-10-23T15:24:50","date_gmt":"2011-10-23T19:24:50","guid":{"rendered":"http:\/\/blogs.nejm.org\/?p=2028"},"modified":"2011-10-23T15:24:50","modified_gmt":"2011-10-23T19:24:50","slug":"tb-timing-of-antiretroviral-therapy-and-being-a-lumper-rather-than-a-splitter","status":"publish","type":"post","link":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/tb-timing-of-antiretroviral-therapy-and-being-a-lumper-rather-than-a-splitter\/2011\/10\/23\/","title":{"rendered":"TB, Timing of Antiretroviral Therapy, and Being a Lumper Rather Than a Splitter"},"content":{"rendered":"<p>Three key papers on timing of ART in patients with TB have <a href=\"http:\/\/www.nejm.org\/toc\/nejm\/365\/16\" target=\"_blank\">just been published<\/a> in the <em>New England Journal of Medicine<\/em>.<\/p>\n<p>Fortunately, Carlos Del Rio has done a bang-up job\u00a0<a href=\"http:\/\/aids-clinical-care.jwatch.org\/cgi\/content\/full\/2011\/1019\/1?q=featured_ac\" target=\"_blank\">summarizing them<\/a> in <em>Journal Watch AIDS Clinical Care.<\/em><\/p>\n<p>And if you&#8217;re wondering how we got our title for Carlos&#8217; piece,\u00a0here&#8217;s an e-mail between our\u00a0Executive Editor to me a few weeks ago:<\/p>\n<blockquote><p>Hi Paul-<br \/>\nLater this month, NEJM will be publishing three articles on the timing of ART initiation relative to\u00a0TB\u00a0treatment. I assume we should cover these?<br \/>\nCath<\/p><\/blockquote>\n<p>To which I responded:<\/p>\n<blockquote><p>Yep. \u00a0And they all can be summarized as follows: &#8220;TB + low CD4 = start ART sooner rather than later&#8221;.<\/p><\/blockquote>\n<p>Yes, there are <em>lots<\/em> more data from these studies than this simple equation, but my response was a reminder that, despite being a thrice-certified ID specialist, I tend to be more of a lumper rather than a splitter &#8212; which makes me feel somewhat deficient in our field.<\/p>\n<p>Oh well.<\/p>\n<p>Of course even the less detail-obsessed\u00a0ID docs like me probably score pretty high on the <a href=\"http:\/\/psychcentral.com\/ocdquiz.htm\" target=\"_blank\">OCD-meter<\/a>, so I can take some comfort in that.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Three key papers on timing of ART in patients with TB have just been published in the New England Journal of Medicine. Fortunately, Carlos Del Rio has done a bang-up job\u00a0summarizing them in Journal Watch AIDS Clinical Care. And if you&#8217;re wondering how we got our title for Carlos&#8217; piece,\u00a0here&#8217;s an e-mail between our\u00a0Executive Editor [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4,5,8,10],"tags":[77,83,423,650,898,951],"class_list":["post-2028","post","type-post","status-publish","format-standard","hentry","category-hiv","category-infectious-diseases","category-patient-care","category-research","tag-antiretroviral-therapy","tag-art","tag-hiv","tag-new-england-journal-of-medicine","tag-tb","tag-tuberculosis"],"post_mailing_queue_ids":[],"_links":{"self":[{"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/posts\/2028","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/comments?post=2028"}],"version-history":[{"count":0,"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/posts\/2028\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/media?parent=2028"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/categories?post=2028"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/tags?post=2028"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}