{"id":333,"date":"2009-04-06T15:53:09","date_gmt":"2009-04-06T20:53:09","guid":{"rendered":"http:\/\/blogs.nejm.org\/?p=333"},"modified":"2015-06-04T15:31:01","modified_gmt":"2015-06-04T19:31:01","slug":"delayed-opening-day-videos-and-more","status":"publish","type":"post","link":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/delayed-opening-day-videos-and-more\/2009\/04\/06\/","title":{"rendered":"Delayed Opening Day Videos, and More"},"content":{"rendered":"<p><a href=\"http:\/\/blogs.nejm.org\/hiv-id-observations\/wp-content\/uploads\/sites\/2\/2009\/04\/fenway_old_color1.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignright size-thumbnail wp-image-337\" title=\"fenway_old_color\" src=\"http:\/\/blogs.nejm.org\/hiv-id-observations\/wp-content\/uploads\/sites\/2\/2009\/04\/fenway_old_color1.jpg\" alt=\"\" width=\"150\" height=\"100\" \/><\/a>Some random HIV\/ID issues while awaiting a delayed opening day here in cold, rainy Boston:<\/p>\n<ul style=\"padding-left: 30px\">\n<li>If you enjoy video highlights, check out <a href=\"http:\/\/www.sciencemag.org\/cgi\/content\/full\/sci;323\/5922\/1743\/DC1\" target=\"_blank\">these<\/a> of HIV making its way from T cell to T cell.\u00a0 If you&#8217;re short on time, #&#8217;s 9-12 are particularly amazing.\u00a0 Still, I don&#8217;t imagine that\u00a0this video will make it to Youtube anytime soon:<\/li>\n<\/ul>\n<blockquote style=\"padding-left: 30px\"><p>Transfer of an entire synaptic button to the CD4+ target cell. Image is an overlay of brightfield image and green fluorescence in a maximum intensity projection of the acquired stack.<\/p><\/blockquote>\n<p style=\"padding-left: 30px\">(Hat tip to J Li for the link.)<\/p>\n<ul style=\"padding-left: 30px\">\n<li><a href=\"http:\/\/content.nejm.org\/cgi\/content\/full\/NEJMoa0807252\" target=\"_blank\">NA-ACCORD lands<\/a>, to be published in print April 30th.\u00a0 After a major study has been presented at a meeting twice, discussed extensively and digested, I sometimes wonder, what is the impact of actual publication?\u00a0 Here I&#8217;d suggest reading the fine print, as the published paper <em>does <\/em>differ in some major ways from what was presented last year at ICAAC and this year at CROI:\u00a0 the beneficial effect of starting earlier (with CD4 &gt; 500) was even greater than reported earlier, but the groups who did start early differed (significantly) from those who deferred.\u00a0 The study&#8217;s impact on clinical practice?\u00a0 We&#8217;ll see, but I suspect it will be substantial given the other data supporting earlier treatment.<\/li>\n<li><a href=\"http:\/\/www.boston.com\/business\/articles\/2009\/04\/06\/sick_bats_pr_problem_could_prove_to_be_deadly\/\" target=\"_blank\">Bats have an image problem<\/a>.\u00a0 A mysterious illness &#8212; white nose syndrome &#8212; is decimating the bat population, and no one cares.\u00a0 Why am I not surprised?\u00a0 Money quote:<\/li>\n<\/ul>\n<blockquote style=\"padding-left: 30px\"><p>To a public raised on vampire movies, bats are loathsome, frightening creatures &#8211; blind, flying rodents that all <a href=\"http:\/\/blogs.nejm.org\/index.php\/2008\/04\/17\/required-reading-bat-related-human-rabies\/\" target=\"_blank\">carry rabies<\/a>, suck human blood, and get impossibly tangled in long hair.<\/p><\/blockquote>\n<p style=\"padding-left: 30px\">(They said it, not me.) Turns out that to garner support for animals, &#8220;cuteness rules&#8221; &#8212; which means that causes for polar bears (global warming) and toucans (rain forests) get much more sympathy (and $$$) than bats.<\/p>\n<ul style=\"padding-left: 30px\">\n<li>But I love <a href=\"http:\/\/news.google.com\/news?hl=en&amp;rls=com.microsoft:en-us&amp;rlz=1I7GGLD_en&amp;ei=Md3ZSfGIDdHrlQe46uzcDA&amp;resnum=0&amp;q=pistachio+nuts&amp;um=1&amp;ie=UTF-8&amp;ei=M93ZSYLZEZXglQfCtf3KDA&amp;sa=X&amp;oi=news_group&amp;resnum=1&amp;ct=title\" target=\"_blank\">pistachio nuts!<\/a> Oh well.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Some random HIV\/ID issues while awaiting a delayed opening day here in cold, rainy Boston: If you enjoy video highlights, check out these of HIV making its way from T cell to T cell.\u00a0 If you&#8217;re short on time, #&#8217;s 9-12 are particularly amazing.\u00a0 Still, I don&#8217;t imagine that\u00a0this video will make it to Youtube [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3,4,5,8],"tags":[104,244,478,675,725,735,775,778,896,933],"class_list":["post-333","post","type-post","status-publish","format-standard","hentry","category-health-care","category-hiv","category-infectious-diseases","category-patient-care","tag-bat-population","tag-croi","tag-icaac","tag-opening-day","tag-pistachio-nuts","tag-polar-bears-global-warming","tag-rabies","tag-rain-forests","tag-target-cell","tag-toucans"],"post_mailing_queue_ids":[],"_links":{"self":[{"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/posts\/333","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/comments?post=333"}],"version-history":[{"count":0,"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/posts\/333\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/media?parent=333"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/categories?post=333"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/tags?post=333"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}