{"id":7763,"date":"2015-10-07T22:40:03","date_gmt":"2015-10-08T02:40:03","guid":{"rendered":"http:\/\/blogs.nejm.org\/hiv-id-observations\/?p=7763"},"modified":"2015-10-07T22:40:03","modified_gmt":"2015-10-08T02:40:03","slug":"the-future-of-diagnostic-microbiology-in-17-minutes","status":"publish","type":"post","link":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/the-future-of-diagnostic-microbiology-in-17-minutes\/2015\/10\/07\/","title":{"rendered":"The Future of Diagnostic Microbiology, in 17 Minutes!"},"content":{"rendered":"<p><a href=\"http:\/\/blogs.nejm.org\/hiv-id-observations\/wp-content\/uploads\/sites\/2\/2015\/10\/maldi-tof-principle.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignright size-medium wp-image-7766\" src=\"http:\/\/blogs.nejm.org\/hiv-id-observations\/wp-content\/uploads\/sites\/2\/2015\/10\/maldi-tof-principle-300x170.jpg\" alt=\"maldi-tof-principle\" width=\"300\" height=\"170\" srcset=\"https:\/\/blogs.nejm.org\/hiv-id-observations\/wp-content\/uploads\/sites\/2\/2015\/10\/maldi-tof-principle-300x170.jpg 300w, https:\/\/blogs.nejm.org\/hiv-id-observations\/wp-content\/uploads\/sites\/2\/2015\/10\/maldi-tof-principle.jpg 410w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/a>Over at <em><a href=\"http:\/\/ofid.oxfordjournals.org\/\" target=\"_blank\">Open Forum Infectious Diseases<\/a><\/em>, I had the pleasure\u00a0to interview Dr. Angela Caliendo about the latest advances in diagnostic microbiology.\u00a0She touches on molecular testing in general, rapid pathogen identification (especially with <a href=\"http:\/\/cmgm.stanford.edu\/pan\/PANpix\/ms\/MALDI%20animation\/maldi_animation_large.gif\" target=\"_blank\">MALDI-TOF<\/a>, everyone&#8217;s favorite acronym), &#8220;syndromic&#8221; diagnostic testing for respiratory infections and diarrhea, use of Xpert for TB even here in the United States, and, of course the cost of implementing\u00a0all these new technologies.<\/p>\n<p>It&#8217;s incredibly entertaining, especially\u00a0for ID geeks like me, and that&#8217;s because of the person I&#8217;m interviewing. Here are few key facts about Dr. Caliendo:<\/p>\n<ul>\n<li>She goes by Angie.<\/li>\n<li>She&#8217;s Professor of Medicine at Brown, and Vice Chair of the Department of Medicine. Before that, she was the Medical Director\u00a0of the microbiology lab at Emory for 14 years.<\/li>\n<li>She&#8217;s one of those rare individuals\u00a0who understands both the clinical and the laboratory side of medicine, an\u00a0MD\/PhD who really does blend both of those degrees.<\/li>\n<li>She&#8217;s an incredible teacher. If you&#8217;re looking for a Grand Rounds speaker on an ID topic, look no further!<\/li>\n<li>She&#8217;s been a major driver in the effort to improve diagnostics in Infectious Diseases, and was the lead author in this <a href=\"http:\/\/cid.oxfordjournals.org\/content\/57\/suppl_3\/S139.long\" target=\"_blank\">widely cited position paper.<\/a><\/li>\n<\/ul>\n<p>Angie and I were medical residents and ID fellows together (a few years ago, ahem), and I can only remember one weakness (if you can call it that) &#8212; she has a horrible sense of direction. Really hopeless. I once told her to drive &#8220;towards the river&#8221; two blocks away from the Charles, and she looked at me as if I&#8217;d asked her to navigate to Mars. She admitted that she only knew where the river was if she could literally\u00a0<em>see<\/em> it<i>.\u00a0<\/i><\/p>\n<p>Aside from that, however, working with Angie was all gold.<\/p>\n<p>Interview <a href=\"http:\/\/www.oxfordjournals.org\/our_journals\/ofid\/caliendomicrolabsinterview.mp3\" target=\"_blank\">here<\/a>, transcript <a href=\"http:\/\/www.oxfordjournals.org\/our_journals\/ofid\/caliendo_interview_by_paul_sax_final.pdf\" target=\"_blank\">here.<\/a><\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Over at Open Forum Infectious Diseases, I had the pleasure\u00a0to interview Dr. Angela Caliendo about the latest advances in diagnostic microbiology.\u00a0She touches on molecular testing in general, rapid pathogen identification (especially with MALDI-TOF, everyone&#8217;s favorite acronym), &#8220;syndromic&#8221; diagnostic testing for respiratory infections and diarrhea, use of Xpert for TB even here in the United States, [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3,5,8,10],"tags":[1079,616,1082],"class_list":["post-7763","post","type-post","status-publish","format-standard","hentry","category-health-care","category-infectious-diseases","category-patient-care","category-research","tag-maldi-tof","tag-microbiology","tag-xpert"],"post_mailing_queue_ids":[],"_links":{"self":[{"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/posts\/7763","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/comments?post=7763"}],"version-history":[{"count":0,"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/posts\/7763\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/media?parent=7763"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/categories?post=7763"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/tags?post=7763"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}