{"id":9819,"date":"2020-09-27T14:51:38","date_gmt":"2020-09-27T18:51:38","guid":{"rendered":"https:\/\/blogs.nejm.org\/hiv-id-observations\/?p=9819"},"modified":"2020-09-28T06:24:26","modified_gmt":"2020-09-28T10:24:26","slug":"humbled-but-still-hopeful","status":"publish","type":"post","link":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/humbled-but-still-hopeful\/2020\/09\/27\/","title":{"rendered":"Humbled &#8212; But Still Hopeful"},"content":{"rendered":"<div id=\"attachment_9822\" style=\"width: 298px\" class=\"wp-caption alignright\"><a href=\"https:\/\/blogs.nejm.org\/hiv-id-observations\/wp-content\/uploads\/sites\/2\/2020\/09\/44013006465_cef1147af4_b.jpg\"><img loading=\"lazy\" decoding=\"async\" aria-describedby=\"caption-attachment-9822\" class=\" wp-image-9822\" src=\"https:\/\/blogs.nejm.org\/hiv-id-observations\/wp-content\/uploads\/sites\/2\/2020\/09\/44013006465_cef1147af4_b.jpg\" alt=\"\" width=\"288\" height=\"432\" srcset=\"https:\/\/blogs.nejm.org\/hiv-id-observations\/wp-content\/uploads\/sites\/2\/2020\/09\/44013006465_cef1147af4_b.jpg 567w, https:\/\/blogs.nejm.org\/hiv-id-observations\/wp-content\/uploads\/sites\/2\/2020\/09\/44013006465_cef1147af4_b-200x300.jpg 200w\" sizes=\"auto, (max-width: 288px) 100vw, 288px\" \/><\/a><p id=\"caption-attachment-9822\" class=\"wp-caption-text\">A Promenade through the Sky, from Le Magasin pittoresque, June 1847.<\/p><\/div>\n<p>When Dr. Anthony Fauci <a href=\"https:\/\/partners.mediasite.com\/mediasite\/Play\/968f633a874c4f1a80c368496f49d4661d\" target=\"_blank\" rel=\"noopener noreferrer\">joined us earlier this month for a virtual medical grand rounds<\/a>, several of my colleagues participated. At the end, each was asked to comment about what they had learned so far from the COVID-19 pandemic.<\/p>\n<p>Dr. Michael Klompas, our brilliant hospital epidemiologist, wisely answered:<\/p>\n<p style=\"padding-left: 40px\"><em>Humility.<\/em><\/p>\n<p>His answer resonated strongly again, because this week our hospital <a href=\"https:\/\/www.brighamandwomens.org\/about-bwh\/newsroom\/press-releases-detail?id=3684\" target=\"_blank\" rel=\"noopener noreferrer\">is facing a cluster of cases<\/a> on our inpatient service.<\/p>\n<p>I want to underscore that Mike and our infection control team have worked tirelessly on our COVID-19 response right from the first moment we heard about it in January &#8212; longer than anyone. They have done an exemplary job, providing transparent and evidenced-based guidance. They have done everything they can to keep our patients safe, and bring us to work safely as well.<\/p>\n<p>The clinical staff &#8212; doctors, nurses, respiratory therapists, pharmacists, physical therapists, social workers, dieticians &#8212; adhere to infection control policies. Same for other essential workers delivering food, cleaning the rooms, working in the cafeteria, transporting patients.<\/p>\n<p>But we humans are, well, human. Meaning not perfect. Nor are systems created by humans perfect. We are constantly learning. To pretend otherwise would be hubris.<\/p>\n<p>And our cluster is a reminder that this is a tricky virus. As some have said, the Goldilocks&#8217; porridge of viruses when it comes to how it spreads.<\/p>\n<p>Not so universally severe that it can be diagnosed and contained once identified &#8212; like Ebola, SARS, MERS.<\/p>\n<p>Not so well-understood from a transmission perspective that cases can be prevented through avoiding exposures and targeted immunization &#8212; rabies.<\/p>\n<p>Not so mild in most people that we can tolerate nearly universal infection &#8212; Epstein-Barr virus.<\/p>\n<p>To cause a pandemic, the likes of which we haven&#8217;t seen in over a century, SARS-CoV-2 has to be <em>just right.<\/em><\/p>\n<p>It causes a mild infection in most (not all) young people; becomes progressively more serious as we age; takes advantage of those with common comorbidities (diabetes, high blood pressure, obesity); and &#8212; here is the crucial factor &#8212; spreads to others before we have symptoms.<\/p>\n<p>Or even have no symptoms at all.<\/p>\n<p>Now, as the hospital tests literally thousands of employees, sequences the virus, does engineering analyses, and conducts behavioral interviews, we&#8217;ll optimally learn what happened with this cluster so we can prevent it from happening again &#8212; both here and elsewhere.<\/p>\n<p>Yes, humbled. But optimistic that with continued transparency about what we find, there will be progress.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>When Dr. Anthony Fauci joined us earlier this month for a virtual medical grand rounds, several of my colleagues participated. At the end, each was asked to comment about what they had learned so far from the COVID-19 pandemic. Dr. Michael Klompas, our brilliant hospital epidemiologist, wisely answered: Humility. His answer resonated strongly again, because [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3,5],"tags":[4601],"class_list":["post-9819","post","type-post","status-publish","format-standard","hentry","category-health-care","category-infectious-diseases","tag-covid-19"],"post_mailing_queue_ids":[],"_links":{"self":[{"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/posts\/9819","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/comments?post=9819"}],"version-history":[{"count":0,"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/posts\/9819\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/media?parent=9819"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/categories?post=9819"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.nejm.org\/hiv-id-observations\/index.php\/wp-json\/wp\/v2\/tags?post=9819"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}