Posts Tagged ‘estrogen’

Anastrozole and Fulvestrant in Breast Cancer

Posted by • August 3rd, 2012

A new study from Mehta and others shows the combination of anastrozole and fulvestrant — which interfere with estrogen signaling by distinct mechanisms — increases progression-free and overall survival as compared with anastrozole alone or anastrozole followed by fulvestrant in women with HR-positive breast cancer. Endocrine therapy plays a central role in the treatment of hormone-receptor (HR)-positive… Read More…

Arterial Thrombosis and Hormonal Contraception

Posted by • June 15th, 2012

In a study of Danish women, oral contraceptive pills containing estrogen and progestin were associated with increased risks of stroke and myocardial infarction (MI). Variations in risk according to estrogen dose and progestin type were modest. The risk of thromboembolic complications with the use of hormonal contraception is an important issue scientifically and is relevant for… Read More…