Posts Tagged ‘HCV’

Men Who Have Sex with Men

Posted by • August 28th, 2015

A new Clinical Practice article covers primary care for men who have sex with men. Care should include a detailed sexual history to assess the risk of infection with HIV, the use of preexposure prophylaxis for those at high risk, and appropriate vaccinations and regular testing for sexually transmitted infections. Men who have sex with men,… Read More…

Ledipasvir–Sofosbuvir for Previously Treated HCV

Posted by • April 16th, 2014

The old adage, “The more things change, the more they stay the same,” simply does not apply when it comes to the treatment of hepatitis C virus (HCV). The mainstay of HCV treatment for many years has included interferon (peginterferon, since 2001) and ribavirin. While relatively effective for patients with HCV genotypes 2 and 3,… Read More…

Hepatitis C Virus Infection

Posted by • May 17th, 2013

Only 20 years after the discovery of the hepatitis C virus, a cure is now likely for most people with chronic infection. The latest review in our Drug Therapy series considers current therapy and the present landscape of drug development for hepatitis C. The hepatitis C virus (HCV) carries a substantial disease burden, not only in… Read More…

Arthritis and Rash

Posted by • March 29th, 2013

In the latest Case Record of the Massachusetts General Hospital, a 30-year-old man with a history of IV drug use was admitted to this hospital because of fever, myalgias, polyarthritis, and rash. Results of liver-function tests were notable for mildly elevated hepatic aminotransferase levels and a normal bilirubin level. Adulterants are compounds added to street drugs… Read More…

Treatment of Hepatitis C

Posted by • January 19th, 2012

In a new study of 21 patients with hepatitis C virus genotype 1 infection who had had no response to prior treatment, sustained virologic responses were achieved in 4 of 11 who were treated with two antiviral agents alone and in 9 of 10 who were treated with the antiviral agents plus peginterferon and ribavirin. Approximately… Read More…

A Better Way to Unbind Prometheus? Boceprevir for the Treatment of Chronic Hepatitis C Infection

Posted by • March 30th, 2011

What do Mickey Mantle, Evel Knievel, and Pamela Anderson have in common? Infamy, certainly, but all three are also reported to have battled chronic hepatitis C virus (HCV) infection. And they aren’t alone: Including a sizable list of celebrities, it is estimated that 160 million people worldwide have the disease, putting them at risk of… Read More…