Posts Tagged ‘HMG-CoA’

Statin-Associated Autoimmune Myopathy

Posted by • February 19th, 2016

Statins significantly reduce the incidence of cardiovascular disease, are generally safe, and have an acceptable side-effect profile. It is now recognized, however, that in very rare cases, an autoimmune myopathy develops in patients treated with statins; this disorder is characterized by muscle weakness, evidence of muscle-cell necrosis on biopsy, and the presence of autoantibodies against… Read More…

Simvastatin in the Acute Respiratory Distress Syndrome

Posted by • October 31st, 2014

In a recent study, patients with acute respiratory distress syndrome who were not receiving statins were assigned to receive simvastatin or placebo. At 28 days, there were no significant between-group differences in survival or in the number of ventilator-free days. The acute respiratory distress syndrome (ARDS) is a common, devastating clinical syndrome characterized by life-threatening respiratory… Read More…