Posts Tagged ‘hyperpigmentation’

12-Year-Old Girl with Irritability and Insomnia

Posted by • May 24th, 2013

In the latest Case Record of the Massachusetts General Hospital, a 12-year-old girl with a history of celiac disease, anxiety, and depression was seen in the outpatient psychiatry clinic of this hospital because of irritability, hypersomnia, and multiple somatic symptoms. Psychotherapy and the administration of antidepressants were begun. Pediatric patients with somatization are likely to have… Read More…

Vitamin B12 Deficiency

Posted by • January 11th, 2013

Vitamin B12 deficiency causes reversible megaloblastic anemia, demyelinating disease, or both. Current assays have insufficient sensitivity and specificity; methylmalonic acid levels are useful to confirm diagnosis. Parenteral or highdose oral vitamin B12 is effective therapy.  The latest article in our Clinical Practice series, Vitamin B12 Deficiency, comes from Dr. Sally P. Stabler at the University… Read More…