Posts Tagged ‘LABA’

A New Combination Therapy to Help Prevent COPD Exacerbations?

Posted by • June 8th, 2016

You walk into your office to see, once again, Mr. Jones, at 64-year-old male who suffers from chronic obstructive pulmonary disorder (COPD). Mr. Jones is recovering from a recent visit to the ED due to his third COPD exacerbation event this year. He’s frustrated with his recurrent COPD exacerbations, and wants to know if his… Read More…

Tiotropium and the ancient datura plant: Revisiting the role of antimuscarinic therapy in asthma

Posted by • September 6th, 2012

For centuries the datura plant has been used for treatment of respiratory disease. The plant, also known as jimson weed or devil’s trumpet, is a potent member of the alkaloid family with antimuscarinic properties. American physicians in the 19th century would commonly recommend patients to smoke datura leaves for relief of asthma and obstructive airway… Read More…

Wind of Change? The TALC Trial Blows into Town

Posted by • October 27th, 2010

You’re an asthmatic.  You’re on low-dose inhaled corticosteroids (ICS) and you’ve addressed all the lifestyle modifications that your doctor has recommended, but you’re still symptomatic almost every day.  It’s clearly time to step-up treatment – but step-up to what?  You could increase your ICS dose, or add an inhaled long-acting beta agonist (LABA), or even… Read More…

Step-up Therapy for Children with Uncontrolled Asthma Receiving Inhaled Corticosteroids

Posted by • March 17th, 2010

Evidence to guide step-up therapy for children whose asthma is poorly controlled by low-dose inhaled corticosteroids (ICS) has been lacking. In a crossover study of 182 children, Lemanske et al. attempt to determine which step-up therapy is best, and whether it can be predicted which therapy will induce a better response in a particular child. For… Read More…