Posts Tagged ‘mastectomy’

Prospective Validation of a 21-Gene Expression Assay (OncotypeDX) in Breast Cancer

Posted by • November 18th, 2015

Imagine it is 1970. You are a 50-something year old woman and your doctor has just palpated a 1 cm mass in your left breast.  What are your options for treatment?  Unfortunately, radical mastectomy, introduced by Dr. William Halsted in 1894, remained the standard of care at that time.  Breast cancer treatment as it was… Read More…

Vote for the Most Important Article, 1980-1989

Posted by • June 1st, 2012

For the most important advance during the early years of NEJM, you voted for the beginning of ether anesthesia. From 1880-1929, it was the first description of platelets, and from 1930-1959, the beginning of bone marrow transplantation. The 1960s brought us studies on an attenuated measles vaccine, and the first oral ACE inhibitor was introduced… Read More…