Posts Tagged ‘multiple myeloma’

Daratumumab for Myeloma

Posted by • October 6th, 2016

The incorporation of proteasome inhibitors and immunomodulatory drugs into the standard of care has improved outcomes in patients with multiple myeloma over the past 10 years, but most patients still eventually have a relapse. In the October 6, 2016, issue of the New England Journal of Medicine, Dimopoulos et al. report the results of a… Read More…

A Man with Multiple Myeloma and Skin Tightness

Posted by • March 13th, 2015

In the latest Case Record of the Massachusetts General Hospital, a 68-year-old man was seen in the rheumatology clinic because of increasing skin tightness, joint pain, and edema of the hands and feet. Nine months earlier, he had received a diagnosis of multiple myeloma and had undergone autologous stem-cell transplantation. Fibrosing dermopathies are a group of… Read More…

Myeloma

Posted by • September 23rd, 2011

In the latest Case Record of the Massachusetts General Hospital, cardiac and renal failure developed in a 66-year-old woman. Echocardiography suggested infiltrative cardiomyopathy, lytic bone lesions were seen on imaging, and elevated serum free light chains were detected. A diagnostic procedure was performed.                 Categories of plasma-cell neoplasms include monoclonal gammopathy of unknown significance (MGUS), asymptomatic plasma-cell… Read More…

Multiple Myeloma

Posted by • March 18th, 2011

The latest article in our Medical Progress series, Multiple Myeloma, comes from Dr. Antonio Palumbo at the University of Turin, and Dr. Kenneth Anderson at Harvard Medical School and Dana-Farber Cancer Institute. Multiple myeloma is a neoplastic plasma cell disorder characterized by clonal proliferation of malignant plasma cells in the bone marrow microenvironment, monoclonal protein in… Read More…